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Clinical Trial Summary

The goal of this research study is to establish chimerism and avoid graft-versus-host disease in patients with hemoglobinopathies.


Clinical Trial Description

This proposal is a phase I/II feasibility study to demonstrate that mixed chimerism can be established with minimal risk in recipients with hemoglobinopathies treated with Campath-1H-based nonmyeloablative conditioning and graft engineering to reduce the risk of Graft Versus Host Disease (GVHD), but preserve engraftment of donor cells. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT01419704
Study type Interventional
Source Talaris Therapeutics Inc.
Contact
Status Withdrawn
Phase Phase 1/Phase 2
Start date May 2011
Completion date May 2016

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