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Tachycardia clinical trials

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NCT ID: NCT01075581 Not yet recruiting - Hypertension Clinical Trials

Intranasal Injection Versus Topical Administration of Epinephrin During Endoscopic Sinus Surgery

Start date: April 2010
Phase: N/A
Study type: Interventional

Intranasal injection of epinephrine is used routinely during endoscopic sinus surgery (ESS) to reduce bleeding in the nasal mucosa and thereby improve visualization of the surgical field. However, systemic absorption of epinephrine via the nasal mucosa is often accompanied by cardiovascular side effects during the early postinjection period, putting in risk patients with cardiovascular morbidity. Evidence indicate that topical administration of epinephrine achieves similar hemostatic effects compared with injection of epinephrine, while avoiding systemic adverse effects. We wish to conduct a prospective controlled trial assessing the hemostatic and hemodynamic effects of intranasal injection compared to topical application of epinephrin during ESS, in order to evaluate whether the previous could be avoided due to its untoward effects. We hypothesize that topical administration of epinephrine provides a hemostatic effect not inferior to that of intranasal injection while minimizing hemodynamic instability during ESS.

NCT ID: NCT01074749 Terminated - Clinical trials for Paroxysmal Atrial Fibrillation

Optimal Sensing in Atrial Tachyarrhythmia's Study

OSAT
Start date: July 2010
Phase: N/A
Study type: Interventional

The aim of the study is the comparison of two different leads in their capabilities to detect episodes and duration of paroxysmal atrial fibrillation (AF) and atrial tachyarrhythmia (AT), and the rejection of far field sensing of the far field R-wave (FFRW).

NCT ID: NCT01064739 Completed - Healthy Volunteers Clinical Trials

Renal Salt Handling in Postural Tachycardia Syndrome Following Dietary Dopa Administration

Start date: January 2007
Phase: Phase 0
Study type: Interventional

The purpose of this study is to learn how plants can play a role in gain/loss of sodium in the urine and in the regulation of blood pressure. Dopamine is a chemical mostly present in the brain and kidneys which assists in regulation of the body's salts (sodium and potassium). Fava beans contain a lot of the chemical that increases the production of dopamine by the kidneys. The purpose of these studies is to characterize the diuretic effects of dietary catecholamine sources in healthy individuals. Specific aims are: 1. To determine the effect of dietary dopa sources on plasma and urinary catecholamines. 2. To investigate the capacity of botanical dopaminergic agents (fava beans) to induce natriuresis in a short term study. 3. To provide preliminary data on the effects of dietary dopa on heart rate and blood pressure. In these studies, we will test the null hypothesis (Ho) that urinary sodium excretion will not differ in healthy volunteers after consumption of a fixed-sodium study diet and the study diet plus fava beans.

NCT ID: NCT01064076 Active, not recruiting - Clinical trials for Tachycardia, Ventricular

S-ICD® System IDE Clinical Study

Start date: January 2010
Phase: N/A
Study type: Interventional

This clinical study is designed to evaluate the safety and effectiveness of the subcutaneous implantable defibrillator (S-ICD) System.

NCT ID: NCT01045668 Completed - Clinical trials for Ventricular Tachycardia

Ablation of Clinical Ventricular Tachycardia Versus Addition of Substrate Ablation on the Long Term Success Rate of VT Ablation

VISTA
Start date: January 2010
Phase: Phase 3
Study type: Interventional

This study aims to assess whether a combined technique of substrate ablation and ablation of the clinically presenting VT at the site of early activation is superior to ablation of the clinically presenting VT alone, in enhancing long-term success of VT ablation.

NCT ID: NCT01038960 Completed - Clinical trials for Ventricular Tachycardia

Exercise Training in ICD Recipients; Effect on Therapy Delivered, Depression and Anxiety

ETHIC
Start date: April 2008
Phase: Phase 3
Study type: Interventional

Interventional study in patients with ICD. Controlled, open intervention with exercise training. Assessment of changes in physiological and psychological parameters.

NCT ID: NCT01032317 Completed - Atrial Fibrillation Clinical Trials

Study of a New Catheter Using Force Sensing Capabilities for the Treatment of Atrial Fibrillation and Ventricular Tachycardia

EZCF-125
Start date: November 2009
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to study the treatment of Atrial Fibrillation and ischemic Ventricular Tachycardia using a RF ablation catheter with contact force sensing capabilities.

NCT ID: NCT01013714 Recruiting - Clinical trials for Ventricular Tachycardia

Cardiac Sympathetic Denervation for Prevention of Ventricular Tachyarrhythmias

PREVENT VT
Start date: July 26, 2021
Phase: Phase 3
Study type: Interventional

The purpose of this research study is to examine the effect of cardiac sympathetic denervation (CSD) surgery on life threatening abnormal heart rhythms called ventricular tachycardia or ventricular fibrillation that can lead to sudden cardiac death. Subjects will be asked to participate in this research study if they have recurrent ventricular tachycardia (at least one ICD shock for ventricular tachycardia) and have undergone at least one catheter ablation procedure or have ventricular tachycardia or fibrillation that is not ablatable. The goal of this study is to determine whether cardiac sympathetic denervation can prevent these abnormal heart rhythms from occurring and therefore, prevent, ICD shocks which are not only painful, but have been shown to reduce quality of life and/or lead to depression, particularly in the period immediately after the shock.

NCT ID: NCT01006746 Completed - Tachycardia Clinical Trials

Observational Study of Patient Comprehension, Perception, Fears and Appreciation Following Home-Monitoring Implementation

Educ@t
Start date: February 2009
Phase: N/A
Study type: Observational

Describe the mutual influences between trainings realized in implantation centers, medico-technical knowledges, technical implementation, perception, fears and appreciation felt by the patients during Home Monitoring implementation.

NCT ID: NCT01000350 Active, not recruiting - Clinical trials for Postural Tachycardia Syndrome

Intravenous (IV) Saline and Exercise in Postural Tachycardia Syndrome (POTS)

Start date: October 2009
Phase: N/A
Study type: Interventional

The investigators will test whether an intravenous infusion of saline (salt water) will improve the exercise capacity in patients with postural tachycardia syndrome (POTS).