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Clinical Trial Summary

Clinical Study on the Safety and Effectiveness of low-dose chidamide maintenance therapy after allogeneic hematopoietic stem cell transplantation for T-cell acute lymphoblastic leukemia or T-cell lymphomas.


Clinical Trial Description

This is a phase ll, single-center, single-arm clinical study.This study is indicated for high-risk of T-cell acute lymphoblastic leukemia or T-cell lymphomas patients. It aims to evaluate the safety and effectiveness of low-dose chidamide maintenance therapy after allogeneic hematopoietic stem cell transplantation for T-cell acute lymphoblastic leukemia or T-cell lymphomas to prevent relapse. 44 patients will be enrolled. The clinical end points include relapse-free survival, acute or chronic GVHD, non-relapse mortality, and overall survival, etc. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05991973
Study type Interventional
Source Zhejiang University
Contact Yanmin Zhao, PhD
Phone +8615858199217
Email yanminzhao@zju.edu.cn
Status Recruiting
Phase Phase 2
Start date July 15, 2023
Completion date July 2027

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