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A Safety and Efficacy Study Evaluating CTX130 in Subjects With Relapsed or Refractory T or B Cell Malignancies (COBALT-LYM)

T Cell Lymphoma Clinical Trial

Official title:
A Phase 1, Open-Label, Multicenter, Dose Escalation and Cohort Expansion Study of the Safety and Efficacy of Anti-CD70 Allogeneic CRISPR-Cas9-Engineered T Cells (CTX130) in Subjects With Relapsed or Refractory T or B Cell Malignancies

Clinical Trial Summary

This is a single-arm, open-label, multicenter, Phase 1 study evaluating the safety and efficacy of CTX130 in subjects with relapsed or refractory T or B cell malignancies.

Clinical Trial Description

The study may enroll approximately 45 subjects in total. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04502446
Study type Interventional
Source CRISPR Therapeutics
Contact
Status Active, not recruiting
Phase Phase 1
Start date July 31, 2020
Completion date May 2027
View Details
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