Junctional AV Ablation in CRT-D: JAVA-CRT

Status Completed

Clinical Trial Summary

Cardiac resynchronization therapy (CRT) is a demonstrably effective device intervention for patients with heart failure with reduced ejection fraction and specific indication. However, many patients with heart failure (HF) are unable to maintain sinus rhythm and approximately 30-36% of CRT patients are in atrial fibrillation (AF).

Clinical Trial Description

This study is designed to evaluate if patients with AF indicated for CRT will have significant reduction in left ventricular end-systolic volume when randomized to atrioventricular junction (AVJ) ablation. In this study, subjects will be randomized to receive CRT-D or CRT-D with AVJ ablation. Randomization will be stratified by enrolling center (1:1 ratio). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02946853
Study type	Interventional
Source	University of Rochester
Contact
Status	Completed
Phase	N/A
Start date	October 1, 2016
Completion date	August 31, 2020

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