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Clinical Trial Summary

This is an investigator-initiated trial to evaluate the safety and efficacy of anti- CD19-CAR-T cells in the relapse or refractory autoimmune diseases.


Clinical Trial Description

This is an investigator-initiated trial to evaluate the safety and efficacy of anti- CD19-CAR-T cells in the relapse or refractory autoimmune diseases. Study intervention consists of a single infusion of CAR-transduced autologous T cells administered intravenously after a lymphodepleting therapy regimen consisting of fludarabine and cyclophosphamide. Interim analysis will be performed when the last participant finishes the visit of 12 weeks after CAR-T cells infusion. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06420154
Study type Interventional
Source First Affiliated Hospital of Wenzhou Medical University
Contact Jianxin Tu, Master's
Phone +86 18267726068
Email Lstujianxin@163.com
Status Not yet recruiting
Phase Early Phase 1
Start date May 27, 2024
Completion date May 27, 2027

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