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Syndrome clinical trials

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NCT ID: NCT04828239 Recruiting - Clinical trials for Carpal Tunnel Syndrome

Acupuncture Versus Laser Acupuncture for Carpal Tunnel Syndrome

Start date: March 10, 2021
Phase: N/A
Study type: Interventional

Carpal tunnel syndrome (CTS) results from the entrapment neuropathy of median nerve at the wrist, and most cases are idiopathic. So far, there are many treatments were developed (Surgical decompression, local injection of steroids, Wrist splints) but they are not fully satisfactory, other treatment modalities need to be further evaluated. Both Acupuncture and laser acupuncture treatments for CTS have been reported. However, those studies still lack associated evidence to evaluate the efficacy of acupuncture and laser acupuncture. The object of the study is to investigate the efficacy of acupuncture compared with laser acupuncture in patients with mild-to-moderate carpal tunnel syndrome (CTS). Nerve conduction studies (NCS) and global symptom score (GSS) assessment will apply to measure objective changes in this randomized, controlled study.

NCT ID: NCT04817787 Recruiting - Metabolic Syndrome Clinical Trials

Exercise Dose and Metformin for Vascular Health in Adults With Metabolic Syndrome

Start date: November 28, 2017
Phase: Phase 2/Phase 3
Study type: Interventional

Arterial disease is the leading cause of morbidity/mortality in Metabolic syndrome (MetS). This occurs early as evidenced by arterial dysfunction that, in turn, raises blood pressure and glucose. Health organizations recommend exercise in an intensity based manner to promote cardiovascular adaptation and prevent disease. Metformin is a common anti-diabetes medication that reduces future type 2 diabetes and cardiovascular risk. However, the optimal exercise dose to be combined with metformin for additive effects on vascular function is unknown. Based on the investigator's preliminary work, the overall hypothesis is that metformin blunts adaptation following high intensity exercise training (HiEx) by lowering mitochondrial derived oxidative stress signaling. The investigators further hypothesize that low intensity exercise (LoEx) training combined with metformin will promote additive effects on vascular function compared to LoEx or HiEx+metformin, and maintain/improve non-exercise physical activity patterns. In this double-blind trial, obese 30-60y MetS participants will be randomized to: 1) LoEx+placebo; 2) LoEx+metformin, 3) HiEx+placebo; or 4) HiEx+metformin for 16 weeks.

NCT ID: NCT04813757 Recruiting - Scapular Dyskinesis Clinical Trials

Scapular Upward Rotation Focused Treatment for Patient With Shoulder Impingement Syndrome and a Positive Scapular Assistance Test

Start date: July 1, 2020
Phase: N/A
Study type: Interventional

Altered scapular movement is a common impairment among patients with subacromial impingement syndrome (SAIS). Nevertheless scapular focused interventions have resulted in conflicting findings among this population. One possible reason for this is the inability to identify patients with SAIS who will respond favorably to a scapular focused intervention. The scapular assistance test (SAT) may be one possible indicator of patients most likely to benefit from a scapular focused intervention, particularly one that emphasizes scapular upward rotation. The purpose of this study is to examine targeted upward rotation intervention in patients demonstrating a positive Scapular Assistance test.

NCT ID: NCT04811287 Recruiting - Clinical trials for Carpal Tunnel Syndrome

PRP as Adjuvant Treatment to CTR for Severe CTS Tunnel Syndrome

Start date: October 15, 2021
Phase: N/A
Study type: Interventional

This study assesses the potential benefit of adjuvant platelet-rich plasma (PRP) with carpal tunnel release (CTR) for patients with severe carpal tunnel syndrome (CTS). CTR is a rather common procedure performed and seems to be quite effective for those with moderate CTS, but a number of patients with severe CTS do not have quite the same response post-CTR. The investigators will recruit patients who fall into the severe CTS category and compare CTR with and without adjuvant PRP to see if PRP can improve outcomes of this common surgery.

NCT ID: NCT04806555 Recruiting - Clinical trials for Compartment Syndrome of Leg

Diagnostic Value of Compression Ultrasound to Detect Acute Compartment Syndrome After Lower Limb Revascularisation

Start date: February 1, 2021
Phase: N/A
Study type: Interventional

Acute compartment syndrome (ACS) after revascularization for acute limb ischemia is a potentially limb-threatening condition and requires urgent fasciotomy. Compression ultrasound (CU) is an established method for measuring intravenous pressure in superficial veins and, for example, can determine central venous pressure in critically ill patients. In cadaver studies, compression ultrasound has been proven to correlate with invasive intra compartmental pressure (ICP) measurements. This study aims to determine CU's added diagnostic value compared to ICP in detecting ACS after revascularisation.

NCT ID: NCT04806490 Recruiting - Clinical trials for Yin Deficiency Syndrome

Standard Scale for Syndrome Differentiation of Yin Deficiency Syndrome

SFYDS
Start date: May 21, 2019
Phase:
Study type: Observational [Patient Registry]

An version of the standard scale for syndrome differentiation of Yin Deficiency Syndrome is not available yet for Chinese medicine. The aim of this study is to develop and validate the standard scale for syndrome differentiation of Yin Deficiency Syndrome. The study is divided into two steps. The first step is to develop the standard scale for syndrome differentiation of Yin Deficiency Syndrome through expert consultation (Delphi method). The second step is to apply the scale in the participants and find out the diagnostic cut-off value of the scale by comparing it with the gold standard.

NCT ID: NCT04806386 Recruiting - Fecal Incontinence Clinical Trials

The Role of Fiber in the Prevention and Treatment of Fecal Incontinence

Start date: July 21, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the effect of fiber supplementation on the fecal metagenome and metabolome in relation to symptoms and anorectal physiology in post-menopausal women with irritable bowel syndrome with diarrhea suffering from liquid stool fecal incontinence (FI.)

NCT ID: NCT04806256 Recruiting - Dry Eye Syndromes Clinical Trials

CDSS of Traditional Chinese Medicine Intervention for Dry Eye Syndrome

Start date: July 11, 2020
Phase: N/A
Study type: Interventional

This project is based on artificial intelligence (AI) algorithms to screen the effective methods of traditional Chinese medicine intervention for dry eye and its applicable conditions, and optimize the traditional Chinese medicine intervention plan for dry eye through the evaluation of evidence-based medicine and expert consensus, and construct the Clinical Decision support system of traditional Chinese medicine intervention for dry eye, secondly, a real-world prospective cohort study design is adopted, the CDSS system is used in the ophthalmology clinic, and its practical application effect on patients with dry eye is evaluated.

NCT ID: NCT04805385 Recruiting - Tourette's Syndrome Clinical Trials

Effects of Lactobacillus Plantarum PS128 in Patients With Tourette's Syndrome

Start date: November 29, 2021
Phase: N/A
Study type: Interventional

To evaluate whether supplementing with PS128 can improve the symptoms and quality of life related to Tourette's disease in children.

NCT ID: NCT04804943 Recruiting - Clinical trials for Acute Respiratory Distress Syndrome

Pilot Clinical Study of NOA-001 for ARDS (Acute Respiratory Distress Syndrome)

Start date: May 22, 2021
Phase: N/A
Study type: Interventional

The primary object of this clinical study is to investigate the efficacy and the safety of NOA-001 in patients with ARDS (ARDS caused by Non-COVID-19 or COVID-19).