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Surgical Wound clinical trials

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NCT ID: NCT06014411 Recruiting - Surgical Wound Clinical Trials

Early Versus Delayed Bathing of Orthopaedic Surgical Wounds

EVDB
Start date: January 29, 2024
Phase: N/A
Study type: Interventional

This is a single center randomized control trial assessing the effect of early versus delayed bathing on orthopaedic surgical wounds in patients undergoing surgical treatment of fractures. Patients will be recruited by screening all patients undergoing surgical treatment for fractures at our institution. Patients who provide written consent will be randomized to one of two treatment arms after confirming eligibility criteria. Group A will be advised to begin early normal bathing (non-submerged showering) with uncovered surgical wounds. Group B will be advised to follow traditional delayed bathing with covered wounds. Those who do not wish to participate in the randomized trial will be invited to participate observationally (no randomization) and have the same prospective follow-up.

NCT ID: NCT05989386 Recruiting - Clinical trials for Surgical Site Infection

Outcomes of High-volume Saline Irrigation VS Povidone-Iodine Solution Cleaning of IOWI in Preventing SSIs in Emergency Laparotomies

Start date: April 29, 2023
Phase: Phase 2/Phase 3
Study type: Interventional

The goal of this clinical trial is to compare the outcomes of High-volume saline irrigation vs Povidone-iodine solution cleaning of the intraoperative incision wound in preventing superficial surgical site infections in patients undergoing emergency laparotomies. The main question it aims to answer are: - Incidence of SSI after intervention - Length of hospital stay Participants will be randomly assigned to two groups receiving either of the two groups: Group A: 1000ml of IOWI with saline solution prior to incision closure Group B: The incisional wound will be closed conventionally without irrigation. Researchers will compare groups A( experimental group) and B (control group) to compare the incidence of superficial surgical site infections after intervention.

NCT ID: NCT05981443 Recruiting - Surgical Wound Clinical Trials

An Analysis of Dermabond vs. Non-Absorbable Sutures in Skin Closure for Brow Ptosis Procedures

Start date: August 15, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare Dermabond with non-absorbable sutures in skin closure after brow ptosis surgery. The main questions it aims to answer are: - if Dermabond provides equivalent wound healing compared to conventional non-absorbable skin suture techniques - if Dermabond provides equivalent scar appearance compared to conventional non-absorbable suture techniques - if Dermabond results in equivalent complication rates compared to conventional non-absorbable suture techniques Participants will have be randomly selected to have either Dermabond or non-absorbable suture closure methods. Scar analysis and both participant and provider surveys will be performed to assess the differences between groups, if any.

NCT ID: NCT05977816 Recruiting - Wound Infection Clinical Trials

PROPEL-2: Prophylactic Negative Pressure Wound Therapy in Laparotomy Wounds

PROPEL-2
Start date: July 14, 2023
Phase: N/A
Study type: Interventional

Post-operative wound issues in abdominal surgery have a significant impact on patient outcomes. This study is taking place to investigate if Negative Pressure Wound Therapy (NPWT) dressings reduces Surgical Site Infections, post surgical complications and improves scar appearance compared to standard dressings.

NCT ID: NCT05897723 Recruiting - Surgical Incision Clinical Trials

Fractional Radiofrequency for Reduction of Surgical Scar Formation

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

Safety and Efficacy of Fractional Radiofrequency for the Reduction of Surgical Scar Formation

NCT ID: NCT05840705 Recruiting - Obesity, Morbid Clinical Trials

Approach Modification for Total Knee Arthroplasty in Morbidly Obese Patients

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

The study provides a detailed description of a smaller incision with better visualization in total knee arthroplasty operations

NCT ID: NCT05758168 Recruiting - Scarring Clinical Trials

Aesthetic Outcome of Tie-over Bolster Application in Surgical Wounds

Start date: October 10, 2023
Phase: N/A
Study type: Interventional

When patients have surgery on the head and face, stitches are the standard way to close the wound. Wounds always result in a scar, but doctors are always looking for ways to reduce scarring. Several studies have been done to test ways to close wounds that reduce scarring. One idea is to reduce the tension around the cut. One way to reduce tension is to stitch a small piece of a special gauze over the top of the regular stitches. This procedure is called a "tie-over bolster dressing." As the name implies, this extra dressing "bolsters" the wound closure so that the skin on each side of the cut stays in place. The bolster dressing procedure has been used in the past in special cases, such as when skin grafts are necessary. The bolster dressing helps the skin graft heal by making sure the graft stays exactly in place. Keeping the wound stable with a bolster dressing also reduces bleeding under the wound. For non-grafted wounds, the bolster dressing procedure has not normally been used, and has not been well-studied. In this study the whole wound will be stitched normally and then the bolster dressing will be applied over half of the wound. This will allow us to see if the side with the bolster dressing heals with less scarring.

NCT ID: NCT05728463 Recruiting - Clinical trials for Cholecystectomy, Laparoscopic

Single Incision Laparoscopic Cholecystectomy Compared With Conventional Laparoscopic Cholecystectomy, a Randomized Controlled Clinical Study

Start date: February 6, 2023
Phase: N/A
Study type: Interventional

Laparoscopic cholecystectomy has been accepted and is nowadays considered as the gold standard treatment of gallstones disease. Conventional laparoscopic cholecystectomy (CLC) was defined as three or four port surgery carried out with either French or American position. It reduced post-operative pain and shorten post-operative length of stay compared with open cholecystectomy in a great extent. Single-incision laparoscopic cholecystectomy (SILC) as a revolutionized surgery, the main reason for its widespread use being the following: less post-operative pain, faster recovery, better cosmetics and quicker return to full activities, all resulting in the improvement of post-operative quality of life. SILC uses the umbilicus as a natural orifice allowing easy access to peritoneal cavity, easy conversion to standard laparoscopy and its easy closure, has been widely introduced into the clinical practice for benign gallbladder diseases. SILC can easily hide the surgical scar inside the umbilicus, thus has better cosmetic effect. But the real clinical benefits for patients still remain a matter of debate. In the last 5 years, many studies on SILC have been published, trying to answer the question whether such a new approach is worthwhile or not and whether is safe and cost-effective.Based on the above controversy, we conduct a RCT comparing clinical and peri-operative outcomes, such as quality of life (QOL), of SILC and CLC with the intent to assess the actual indications of the single-incision approach.

NCT ID: NCT05701475 Recruiting - Clinical trials for Surgical Site Infection

Cutibacterium Acnes: Triple Prevention in Shoulder Operations

C3PO
Start date: January 18, 2023
Phase: N/A
Study type: Interventional

Patients planned for shoulder surgery will be identified and contacted for participation. After informed consent is provided, patients will be randomised into one of three groups: pre-operative cutaneous disinfection with iodine (control group), pre-operative cutaneous and subcutaneous disinfection with iodine (double prevention), and pre-operative cutaneous and subcutaneous disinfection with iodine combined with a skin preparation protocol with benzoyl peroxide gel in the days prior to surgery (triple prevention). Bacterial cultures will be collected during surgery of the surgical field and tissue layers. Culture positivity for Cutibacterium Acnes will be compared between the groups as a primary outcome.

NCT ID: NCT05622110 Recruiting - Obesity Clinical Trials

Laparoscopic Incision Closure s in Obese Patients

LICOP
Start date: December 2, 2023
Phase: N/A
Study type: Interventional

Several methods for closure of trocar wounds are known in laparoscopic surgery including mostly transcutaneous or subcuticular suture or adhesive paper tape. Studies comparing laparoscopic incision closure in bariatric population are limited .This is a prospective study that will be conducted in a single tertiary medical center. s obese population comprise most of our surgical candidates, and due to the aforementioned, the aim of our study is to compare the outcomes of both techniques in obese women.