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Inflammatory Mediators of Acute Kidney Injury in Intensive Care — PronMed  

Surgery Clinical Trial

Official title:
Prospective Studie of Inflammatory Markers in Urine, Plasma and Sputum Associated With Acute Kidney Injury

Clinical Trial Summary

Acute kidney injury (AKI) affects more than 50% of patients admitted to the intensive care unit. The most common underlying cause is sepsis. Severe AKI in combination with sepsis is associated with high mortality. The mechanisms for sepsis-induced AKI are largely unknown. Our hypothesis is that the inflammatory response to an infection cause collateral damage to host tissue and contributes to the development of AKI. In this study we want to investigate the presence of novel inflammatory mediators in patients with sepsis, patients subjected to major surgery (sterile inflammation) and non-inflamed patients and correlate their levels with the risk for AKI.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03720860
Study type Observational
Source Uppsala University
Contact Sara Bulow, MD
Phone +46730247414
Email sara.bulow.anderberg@akademiska.se
Status Recruiting
Phase
Start date January 1, 2018
Completion date May 2026
View Details
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