Development and Validation of a Preoperative Frailty Index Using Health Administrative Data

Surgery Clinical Trial

Official title:

Creation, Evaluation and Validation of a Preoperative Frailty Index Using Health Administrative Data: a Population-based Cohort Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03354546
• Other study ID #: DM8
• Status: Completed
• Phase: N/A
• First received: November 17, 2017
• Last updated: November 24, 2017
• Start date: April 1, 2002
• Est. completion date: March 31, 2016

Study information

• Verified date: November 2017
• Source: Ottawa Hospital Research Institute
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The investigators will create a frailty index using health administrative data available for older people having surgery. The index will be based on the Canadian Study of Health and Aging Frailty Index and standard recommendations for creation of frailty indices.

Description:

The investigators will create a frailty index using health administrative data available for older people having surgery. The index will be based on the Canadian Study of Health and Aging Frailty Index and standard recommendations for creation of frailty indices.

Once derived the index will be tested to measure its association with outcomes, as well as its discrimination. Various representations of the frailty index will be tested (primary-as a continuous measure; secondary as a binary, categorical and fractional polynomial variable). Performance in subgroups will also be evaluated,

Recruitment information / eligibility

• Status: Completed
• Enrollment: 200000
• Est. completion date: March 31, 2016
• Est. primary completion date: March 31, 2016
• Accepts healthy volunteers: No
• Gender: All
• Age group: 66 Years and older

Eligibility

Inclusion Criteria:

• Having elective or emergency noncardiac surgery

Exclusion Criteria:

• no provincial health insurance number

Related Conditions & MeSH terms

• Frail Elderly Syndrome
• Outcomes
• Predictive Value of Tests
• Surgery

Intervention

Diagnostic Test:
• Frailty index
A frailty index composed of variables from health administrative data that cover multi-system health issues. Deficits will be coded as present or absent, and the number of deficits present will be divided by the total number of deficits present to provide an overall score between 0-1.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Ottawa Hospital Research Institute

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Survival for one year after surgery	Still being alive (no death date) in the registered persons database	Date of surgery to 365 days after surgery
Secondary	Institutional discharge	Discharge to long term care or continuing care facility at the time of hospital discharge	Date of surgery to date of hospital discharge, or up to one year after surgery (whichever comes first)