Perioperative Use of Serum Creatinine and Postoperative Acute Kidney Injury

Surgery Clinical Trial

— CreaPeriop  

Official title:

Perioperative Use of Serum Creatinine and Postoperative Acute Kidney Injury: an Observational, Monocentric, Retrospective Study to Explore Physicians' Perception and Practice.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04341974
• Other study ID #: CEAVC 13881/2018
• Status: Completed
• Start date: January 1, 2019
• Est. completion date: March 31, 2020

Study information

• Verified date: April 2020
• Source: Careggi Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The perioperative approach adopted in a cohort of adult oncological patients undergoing major abdominal surgery will be described. In particular, the physician's attitude toward use of sCr for identification of patients at risk for PO-AKI will be described, as well as the patients who should be reassessed in the long term for progression toward CKD. The incidence and risk factors associated with PO-AKI and renal function deterioration within a year postoperatively will be also evaluated.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 423
• Est. completion date: March 31, 2020
• Est. primary completion date: January 1, 2020
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Adult patients

• Scheduled for elective surgery

• Surgery for oncological disease

Exclusion Criteria:

• Patients undergoing postoperative chemotherapy

• Patients who died within 12 month after surgery

Related Conditions & MeSH terms

• Acute Kidney Injury
• Cronich Kidney Disease
• Kidney Diseases
• Malignancy
• Surgery
• Wounds and Injuries

Intervention

Diagnostic Test:
• Serum creatinine
Will be described: 1) the number of patients actually screened with postoperative serum creatinine and 2) the number of patients actually screened with the same parameter at the long-term after surgery

Locations

Country	Name	City	State
Italy	Azienda Ospedaliero Universitaria Careggi	Florence

Sponsors (1)

Lead Sponsor	Collaborator
Careggi Hospital

Country where clinical trial is conducted

Italy, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Adoption of serum creatinine as marker of acute kidney injury postoperively	Number of actual patients screened postoperatively	3rd postoperative day
Secondary	Incidence of acute kidney injury	Number of patients with a postoperative diagnostic increase of serum creatinine, in accordance with KDIGO guidelines	3rd postoperative day
Secondary	Adoption of serum creatinine as marker of long term kidney dysfunction	Number of actual patients screened at the long term	12 month after surgery
Secondary	Incidence of long term kidney dysfunction	Number of patients with a long term reduction in GFR greater than 10 ml/min with respect to the baseline	12 month after surgery