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Surgery clinical trials

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NCT ID: NCT03944720 Terminated - Surgery Clinical Trials

Efficacy of Transvaginal Repair for Rectocele

Start date: July 15, 2019
Phase:
Study type: Observational [Patient Registry]

Patients with rectoceles may present a variety of symptoms such as pelvic pressure, obstructive defecation or discomfort during sexual intercourse. The main symptom of the patient probably ends up conditioning if the patient is referred to a gynaecologist or a colorectal surgeon. Different surgical techniques have been described to repair the rectocele. The posterior colporrhaphy is the preferred approach for most gynaecologists, while the transanal repair is the most common approach for the majority of colorectal surgeons. However, the small number of prospective studies, the inconsistent inclusion criteria and the variability of the outcome measures make difficult to know what the ideal surgical approach for a rectocele repair would be. Gynaecologists usually do not assess defecatory function before a rectocele repair, and studies focused on obstructive defecation include patients with other co-existing pathologies (rectal prolapse, rectal intussusception, enterocele) that may influence the success of the repair. Moreover, functional disorders such as the paradoxical contraction of the external anal sphincter or the puborectalis muscle are not systematically reported. On the other hand, many surgeons have questioned the transvaginal approach because it has been reported that patients may present dyspareunia after the surgery, although it is not systematically evaluated. The hypothesis of the investigators is that the transvaginal approach for rectocele repair is an effective treatment for symptoms of obstructive defecation and is not associated with sexual dysfunction when the plication of the puborectalis muscle is not performed.

NCT ID: NCT03922620 Terminated - Surgery Clinical Trials

Liposomal Bupivacaine vs Peripheral Nerve Block

Start date: January 23, 2020
Phase: Phase 4
Study type: Interventional

Liposomal bupivacaine has gained interest in recent literature for its potential to be an effective adjunct to other pain control modalities in a multi-modal approach to post-operative pain control. The goal of this investigation is to compare the efficacy of local administration of liposomal bupivacaine versus the efficacy of a peripheral nerve block in terms of post-operative pain scores after elective ankle and hindfoot surgery. The investigators hypothesize that there will not be a significant difference in the pain scores of these two groups in opioid naïve patients.

NCT ID: NCT03790683 Terminated - Surgery Clinical Trials

Intraoperative Warming During Major Surgical Procedures Using the Esophageal Temperature Management System

Start date: February 11, 2019
Phase: N/A
Study type: Interventional

The aim of this study is to assess the effectiveness of EnsoETM as a supplemental warming device compared to the standard of care warming practice in patients having major surgery.

NCT ID: NCT03754452 Terminated - Surgery Clinical Trials

Evaluation of the Sarcopenia in Hepatobiliary Surgery

SARFO
Start date: November 9, 2018
Phase:
Study type: Observational

The sarcopenia is defined as a loss of muscle mass and a loss of muscle function ( strength or performance). Some studies showed that the sarcopenia increase the postoperative complications and the overall survival in abdominal surgery. But the sarcopenia is not evaluated in the Hepatobiliary surgery. This prospective, monconcentrique study aim to evaluate the prevalence of sarcopenia, and its associated morbimortality in hepatobiliary surgery for malignant or benign tumors.

NCT ID: NCT03727503 Terminated - Surgery Clinical Trials

Casptesia Versus PICCO in Cardiac Surgical Patients in the ICU

Capstesia
Start date: March 27, 2019
Phase: N/A
Study type: Interventional

The goal of this study is to assess the ability of a new smartphone PPV app to predict fluid responsiveness in cardiac surgical patients in the Intensive care unit (in the postoperative period)

NCT ID: NCT03706430 Terminated - Surgery Clinical Trials

Validation of RPVi as a Parameter to Predict Fluid Responsiveness

Start date: September 24, 2018
Phase:
Study type: Interventional

This is a prospective, nonrandomized, sequential data collection study to evaluate the ability of RPVi to predict fluid responsiveness in comparison with other dynamic parameters including stroke volume variation (SVV) and/or pulse pressure variation (PPV).

NCT ID: NCT03681600 Terminated - Surgery Clinical Trials

Observatory of the Quality of Surgical Procedures for Digestive Cancers

Obchir
Start date: January 1, 2018
Phase:
Study type: Observational [Patient Registry]

Surgery for digestive cancers is managed according to quality standards, validated by the scientific community. Despite the diffusion of these standards through the benchmarks of good practice, the results of the surgery remain disparate. In many countries, this "inequality of opportunity" has justified the establishment of quality assurance systems to measure the results of surgery for one or more localizations of digestive cancer. These surgical audit experiments have shown a positive, rapid and cost-effective impact on complication rates, recurrence rates and overall survival even in the absence of interventional measures. The data collected also helped to improve the management of subgroups of patients usually excluded from clinical trials. In Morocco, the National Cancer Prevention and Control Plan provides for the establishment of a quality assurance system with the introduction of a system for monitoring and evaluating the care of patients. This pilot project is part of this framework, for the group of patients who are candidates for surgery for digestive cancers.

NCT ID: NCT03501927 Terminated - Surgery Clinical Trials

Focused Cardiac Ultrasound in Surgery

PreOPFOCUS
Start date: May 7, 2018
Phase: N/A
Study type: Interventional

Mortality and morbidity remain high after non-cardiac surgery. Known risk factors include age, high ASA grade and emergency surgery. Point-of-care focused cardiac ultrasound may elucidate pathology and potential hemodynamic compromise unknown to handling physicians. This study aims to investigate the effects of focused cardiac ultrasound in high-risk patients undergoing non-cardiac surgery with respect to clinical endpoints.

NCT ID: NCT03363009 Terminated - Surgery Clinical Trials

Contribution of Connected Devices in the Follow-up of the Observance of a Prehabilitation Program

Prehab-Connect
Start date: December 4, 2018
Phase: N/A
Study type: Interventional

Poor physical performance and poor nutritional status increase the risk of complications after major surgery. Prehabilitation is the process of enhancing the functional capacity before surgery. A major problem is the adherence of the patients to the physical program. A controlled randomized study is therefore proposed to determine the impact of coaching on functional exercise capacity. All patients will wear connected devices to measure their physical activity. They will be randomized to either a group in which coaching will be adapted to the physical activity, or a control group in which coaching is performed without any information about physical activity

NCT ID: NCT03350269 Terminated - Surgery Clinical Trials

Effect of Lost Wage Reimbursement to Kidney Donors on Living Donation Rates

Start date: November 15, 2017
Phase: N/A
Study type: Interventional

The study is designed as a randomized controlled trial. The investigators hypothesize that kidney transplant recipient candidates whose donors are offered reimbursement of lost wages (treatment arm) will have a higher probability of receiving a living donor kidney transplant than those randomized to no offer of lost wage reimbursement (control arm). The study expects to demonstrate incremental living donor kidney transplants by assisting individuals who wish to be living organ donors but would be otherwise unable to do so due to the obligatory forfeit of income during the evaluation, donation surgery, and post-operative recuperation periods.