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Surgery clinical trials

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NCT ID: NCT06333665 Active, not recruiting - Surgery Clinical Trials

PPIO-007 Correlation Analysis of Type II Diabetes Mellitus on Short-term and Long-term Outcomes of Patients With Esophageal Squamous Cell Cancer Undergoing Minimally Invasive Esophagectomy

Start date: February 20, 2024
Phase:
Study type: Observational

To date, there is controversy as to whether type II diabetes mellitus is associated with adverse short- and long-term outcomes in patients with esophageal squamous cell carcinoma undergoing minimally invasive esophagectomy. At the same time, to the best of our knowledge, the impact of metformin use and glycemic control on short- and long-term outcomes in this patient population is also controversial. Therefore, this study aims to test the hypothesis that diabetes mellitus is associated with reduced survival in patients with esophageal squamous cell carcinoma undergoing minimally invasive esophagectomy and that treatment with metformin and/or good glycemic control (HbA1c<7.0%) is associated with improved survival.

NCT ID: NCT06221995 Active, not recruiting - Surgery Clinical Trials

Energy Expenditure in Patients With Ulcerative Colitis Undergoing Surgery

Start date: September 25, 2023
Phase:
Study type: Observational

A prospective observational study to assess the energy needs of Ulcerative Colitis patients undergoing total proctocolectomy with ileoanal j-pouch anastomosis.

NCT ID: NCT06180239 Active, not recruiting - Surgery Clinical Trials

Segmentectomy vs Lobectomy

Start date: January 1, 2017
Phase:
Study type: Observational

Actual indications for stage Ia NSCLC patients suggest lobectomy and lymphadenectomy. On the other hand, recent studies reported non-inferiority of segmentectomy in case of nodule < 2cm or with ground glass appearance at computed tomography. However, most of these studies did not report specifical analysis on kind of segmentectomy (single or multiple) and kind of lobectomy. Moreover, a specific study on solid nodules only is still missing. For these reasons, the effectiveness of segmentectomy instead lobectomy for every kind of segment or tumor is still to be defined. Aim of this study is to analyze survival outcome in patients underwent single or multiple segmentectomy compared to lobectomy in stage I non small cell lung cancer.

NCT ID: NCT06031155 Active, not recruiting - Quality of Life Clinical Trials

Swedish Esophageal and Cardia Cancer Study

SECC
Start date: April 2001
Phase:
Study type: Observational

The overall objective of this nationwide Swedish project is to identify strategies that can help reduce the suffering and improve the survivorship among patients surgically treated for oesophageal cancer. This objective can be accomplished by a broad research approach that aims to: 1. describe health-related quality of life (HRQL) 2. identify risk factors and preventive actions for poor HRQL

NCT ID: NCT05987579 Active, not recruiting - Surgery Clinical Trials

Surgical Treatment of Stage T3 Squamous Cell Carcinomas of the Scalp

Start date: May 3, 2021
Phase:
Study type: Observational

This study examines tumor- en surgical characteristics of stage T3 cutaneous squamous cell carcinomas on the scalp, diagnosed between 2010 and 2018. Histological data and patient- and tumor characteristics were collected.

NCT ID: NCT05944835 Active, not recruiting - Surgery Clinical Trials

Validation of Numerical Simulation to Predict Proximal Deployment of Standard Stents

ProxSim
Start date: February 15, 2023
Phase:
Study type: Observational

Endoprosthesis treatment of aortic pathologies has become the reference in the vast majority of situations. The success of this treatment is conditioned by the choice of the endoprosthesis which must be as adapted as possible to the anatomy. This choice is currently based on manual geometric measurements performed on the preoperative scanner using conventional image processing software. The morphological result of the implantation of the endoprosthesis in the aorta is obtained by a CT scan carried out postoperatively. This scanner makes it possible to define the positioning of the endoprosthesis, the apposition surfaces between the aorta and the endoprosthesis and to predict the long-term result.

NCT ID: NCT05886387 Active, not recruiting - Surgery Clinical Trials

a Bayesian Analysis of Three Randomised Clinical Trials of Intraoperative Ventilation

Start date: September 22, 2022
Phase:
Study type: Observational

The investigators designed a protocol for a Bayesian unplanned posthoc analysis using the pooled dataset from three large randomized clinical trials. The primary endpoint will be a composite of postoperative pulmonary complications (PPC) within the first seven postoperative days, which reflects the primary endpoint of the original studies. The investigators will carry out a reanalysis of the harmonised database using Bayesian statistics.

NCT ID: NCT05838443 Active, not recruiting - Surgery Clinical Trials

Mindfulness Surgical Pain Outcomes

MNF
Start date: January 1, 2022
Phase: N/A
Study type: Interventional

This will be a prospective randomized study to evaluate novel, clinically feasible, easily deliverable, pragmatic ways of preemptively modifying known CPSP and behavioral risk factors for acute to chronic pain transitions in adolescents before surgery. In addition, it will provide mechanistic insights and build a strong foundation for future large scale interventional studies that can impact outcomes positively in children undergoing surgery.

NCT ID: NCT05832450 Active, not recruiting - Surgery Clinical Trials

Predictive Model to Calculate the Risk of RBC Transfusion in Elective Brain Tumours Resections (TScoreBTR)

TScoreBTR
Start date: March 21, 2021
Phase:
Study type: Observational

To validate a predictive model for the risk of receiving RBCs in this population. This model uses four preoperative values (haemoglobin levels, tumour volume, previous craniotomy in the same spot, and number of craniotomies foreseen). The investigators would like to create an online data collection tool and calculator.

NCT ID: NCT05798585 Active, not recruiting - Surgery Clinical Trials

Comparing Erector Spinae Plane (ESP) and Thoracic Paravertebral (TPV) Block Analgesic Effect After Elective VATS

Start date: March 31, 2023
Phase: N/A
Study type: Interventional

The aim of the study is to compare two different locoregional techniques in VATS.