Pre-warning Risk Scoring System for Sudden Cardiac Death

Status Recruiting

Clinical Trial Summary

The goal of this observational study is to identify potential indicators for pre-warning of sudden cardiac death (SCD), including clinical biochemistry markers, electrocardiogram, echocardiography, MRI and CT imaging values, genetic markers and so on, and further construct a series of multi-parameter assessments of SCD early screening.

Clinical Trial Description

In the past few decades, evidence-based drug and surgical treatment strategies have significantly improved the prevention of sudden cardiac death (SCD), however, a large number of patients with cardiovascular disease still face high risk of SCD, the prognosis of these high-risk SCD patients are still uncertain. Therefore, clinical physicians might need to move towards a multi-parameter assessment of SCD risk pre-warning. Several parameters for risk stratification of arrhythmia, including clinical biochemistry markers, electrocardiogram, echocardiography, imaging, and genetic markers, are crucial for accurate assessment of SCD risk stratification. In addition, the integration of cardiac magnetic resonance parameters and specific CT and ECG information is a future research trend for implementing risk stratification of malignant arrhythmias. In order to further explore the possibility of early warning of SCD, this study aims to include subjects with potential SCD risks, collect relevant potential SCD warning indicators, and then construct an SCD prewarning score system. Afterwards, the investigators will continuously improve the SCD warning score system based on follow-up information, and ultimately summarize an effective set of SCD warning scores and apply them to clinical practice, striving to achieve early warning of SCD and benefiting more people at risk of SCD. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT06440083
Study type	Observational
Source	Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Contact	Yuling Zhang, M.D.,Ph.D.
Phone	+862081332360
Email	zhyul@mail.sysu.edu.cn
Status	Recruiting
Phase
Start date	March 2, 2023
Completion date	December 31, 2027

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT02923726` - Assessment of Primary Prevention Patients Receiving An ICD - Systematic Evaluation of ATP	N/A
Recruiting	`NCT05175937` - REal World Assessment for Patients Implanted With Implantable CardioverTer DefibrIllatOr Using Bluetooth Technology
Completed	`NCT02026102` - A Pilot Trial of Patient Decision Aids for Implantable Cardioverter-Defibrillators (ICDs)	N/A
Completed	`NCT01262508` - Development of Algorithms to Predict Hemodynamic Instability	N/A
Completed	`NCT00998218` - Effect of Ranolazine on Arrhythmias and Microvolt T- Wave Alternans (MVTWA) Patients With LV Dysfunction	Phase 3
Completed	`NCT00845286` - Marathon, Genetics, Inflammation and the Cardiovascular System: MAGIC-Trial	N/A
Active, not recruiting	`NCT00562757` - Prospective Study to Identify Patients at Risk of Dangerous Ventricular Arrhythmias	N/A
Completed	`NCT00622453` - Arrhythmias in Myotonic Muscular Dystrophy	N/A
Completed	`NCT03833843` - Sudden Cardiac Death in Systemic Right Ventricle
Completed	`NCT04024865` - Domperidone and Risk of Serious Cardiac Events in Postpartum Women
Recruiting	`NCT05799833` - Low QRS Voltages in Young Healthy Individuals and Athletes
Recruiting	`NCT05694572` - Post-market Surveillance of Micorport CRM Cardiac Implantable Electronic Devices
Not yet recruiting	`NCT03622307` - Subcutaneous ICD Therapy Combined With VT Ablation for the Secondary Prevention of Sudden Cardiac Death	N/A
Recruiting	`NCT02058771` - Utilising Lifemap to Investigate Malignant Arrhythmia Therapy
Recruiting	`NCT02056509` - The Effect of Chest Compression and Ventilation Coordination During Cardiopulmonary Resuscitation.	N/A
Terminated	`NCT01948206` - Study of Paced QRS Duration as a Marker of Sudden Cardiac Death	N/A
Completed	`NCT01227785` - Next Generation INCEPTA Implantable Cardioverter Defibrillator (ICD) and Cardiac Resynchronization Therapy (CRT-D) Field Following Study	N/A
Completed	`NCT00534300` - Intravenous n-3 Fatty Acids and Ventricular Tachycardia in Patients With Implantable Cardioverter Defibrillator (ICD)-Pacemaker	Phase 1/Phase 2
Terminated	`NCT00524862` - Standard Drug Therapy vs. Implanted Defibrillator for Primary Prevention of Sudden Cardiac Death	N/A
Recruiting	`NCT00181233` - Imaging Techniques for Identifying Factors of Sudden Cardiac Death Risk