Substance Use Disorders Clinical Trial
— A-CRA at SiSOfficial title:
The Effectiveness of A-CRA in Compulsory Institutional Care for Youth - an Independent Randomized Controlled Trial
Youth with substance use disorder (SUD) and socially disruptive behaviour (such as criminality) who are placed in compulsory institutional care are at high risk of continuing a destructive lifestyle into adulthood. There is a pressing need for effective treatment for this group, yet studies are scarce. The empirically supported SUD treatment Adolescent Community Reinforcement Approach, A-CRA, promotes long-term abstinence, increases social stability and decreases co-morbid psychiatric problems for youth ages 12-25. A-CRA is proven to be one of the most effective SUD treatments for youth but has only been evaluated in outpatient care. Given A-CRA's promising results for youth in vulnerable living situations, it is a reasonable treatment to adjust and evaluate in compulsory care. The main objectives are to evaluate the effectiveness of A-CRA, the short- and long-term effects on social-, emotional- and problem behavior and substance use, for youth placed in compulsory institutional care.
Status | Recruiting |
Enrollment | 220 |
Est. completion date | December 30, 2025 |
Est. primary completion date | September 30, 2025 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 16 Years to 21 Years |
Eligibility | Inclusion Criteria: - Age 16-21 - Placed in institutional care - Suffers from SUD and socially disruptive behaviour - Ability to read and understand informed consent and interventions Exclusion Criteria: - Severe cognitive or psychiatric condition preventing the ability to provide informed consent or undergo assessment or interventions - Serious somatic condition requiring acute medical attention |
Country | Name | City | State |
---|---|---|---|
Sweden | Sundbo | Fagersta | Västmanland |
Sweden | Statens institutionsstyrelse, SiS, Johannisberg | Kalix | |
Sweden | Fagersta | Lindome | Västra Götaland |
Sweden | Statens institutionsstyrelse, SiS, Ljungbacken | Uddevalla |
Lead Sponsor | Collaborator |
---|---|
Karolinska Institutet |
Sweden,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Social, emotional and behavioural problems | Measured using the Strengths and Difficulties Questionnaire | 0 weeks, 7 weeks, 14 weeks and at follow-up 1, 3, 6, and 12 months after treatment completion | |
Secondary | Self reported substance use | Self-reported substance use, five questions | 0 weeks, 7 weeks, 14 weeks and at follow-up 1, 3, 6, 12 months after treatment | |
Secondary | Use of alcohol | AUDIT - Alcohol Use Disorders Identification Test (Saunders et al, 1993) | 0 weeks, 14 weeks and at follow-up 1, 6 and 12 months after treatment completio | |
Secondary | Use of illegal drugs | Drug Use Disorders Identification Test (DUDIT; Berman, Bergman, Palmstierna, & Schlyter, 2005) | 0 weeks, 14 weeks and at follow-up 1, 6 and 12 months after treatment completion | |
Secondary | Number of days until the first relapse | Self-reported substance use, five questions | 0 weeks, 7 weeks, 14 weeks and at follow-up 1, 3, 6 and 12 months after treatment completion | |
Secondary | Aggressive behavior | Measured using the Bröset Violent Checklist (Koskela, 2012) | 0 weeks, 7 weeks and 14 weeks and at follow-up 1 month after treatment completion | |
Secondary | Goal directed behavior and values | Bull's-Eye Values Survey (BEVS; Lundgren et al., 2012) | 0 weeks, 7 weeks, 14 weeks and at follow-up 1, 3, 6, 12 months after treatment | |
Secondary | Psychological flexibility | Avoidance and Fusion Questionnaire Short Version (AFQ-Y8; Livheim et al.,2016) | 0 weeks, 7 weeks, 14 weeks and at follow-up 1, 3, 6, 12 months after treatment |
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