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Benzodiazepine Discontinuation in Opioid Agonist Therapy — BZD-OAT  

Substance Use Disorders Clinical Trial

Official title:
Distress Tolerance and Benzodiazepine Discontinuation in Opioid Agonist Therapy, Phase 2

Clinical Trial Summary

The proposed study is a clinical trial, designed to pilot test a Distress Tolerance-Benzodiazepine Discontinuation (DT-BD) intervention for patients on opioid agonist therapy who currently use benzodiazepines. The DT-BD intervention is an adjunctive psychosocial intervention in people seeking to discontinue (BZD) use. The goal of the study is to assess the applicability and feasibility of this intervention through treatment retention and qualitative interviews with four participants who are receiving opioid agonist treatment and who regularly use BZDs.

Clinical Trial Description

This study pilots a 13-week psychosocial intervention paired with a benzodiazepine taper with the aim of assisting individuals receiving OAT discontinue benzodiazepine use. All participants will receive the same benzodiazepine (BZD) discontinuation protocol. The Distress Tolerance-Benzodiazepine Discontinuation (DT-BD) intervention consists of 14 study visits: the first visit consists of the baseline assessment and the first therapy visits, 4 subsequent weekly therapy visits, then a 9-week BZD taper. Some participants may be prescribed non-benzodiazepine medications to treat the underlying conditions for which they were using BZDs [e.g. selective serotonin reuptake inhibitors (SSRI) for anxiety or hypnotics for insomnia]. Data collection will occur starting at the baseline assessment. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04109118
Study type Interventional
Source Boston Medical Center
Contact
Status Completed
Phase Phase 2
Start date March 18, 2021
Completion date July 8, 2021
View Details
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