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NCT04065334 Clinical Trial

Exercise Training as Medicine for Substance Use Disorder Patients

Substance Use Disorders Clinical Trial

Official title:
Effects of Low- Versus High Dose High Intensity Interval Training and Strength Training on Physical Health in Substance Use Disorder Patients: A Randomized Controlled Trial

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT04065334
Other study ID # 2019/502
Secondary ID
Status Recruiting
Phase N/A
First received
Last updated
Start date February 1, 2020
Est. completion date August 2023

Study information
Verified date January 2023
Source St. Olavs Hospital
Contact Henrik Loe, phd
Phone 0047 92093611
Email henrik.loe@stolav.no
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

This study compares the effects of high dose and low dose, high intensity, endurance training and strength training in substance use disorder patients. The hypothesis is that the increase in endurance (measured as maximal oxygen uptake) and strength (measured as maximal strength) will be similar in both the high dose and low dose training groups after 24 training sessions over eight weeks. The rationale for this assumption is based on the patient groups poor physical capacity, supporting that a lesser physical workload is needed to achieve a substantial increase in physical capacity. The practical implication could be higher training attendance, because it is likely easier to motivate the patient group when they only have to perform half the workload. It is paramount for this patient group to increase their physical capacity and consequently augment their physical health status since they are in a high-risk group for developing life-threatening lifestyle related diseases.

Recruitment information / eligibility
Status Recruiting
Enrollment 40
Est. completion date August 2023
Est. primary completion date August 2023
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - Being an inpatient at the clinic - Free of known cardiovascular disease, pulmonary disease and cancer Exclusion Criteria: - Not able to perform a maximal treadmill test - Not able to perform a maximal strength test in hack squat

Study Design

Related Conditions & MeSH terms

Intervention

Behavioral:
• High dose training
4 x 4 minutes of high intensity workload on treadmill and 4 repetitions x 4 sets of high intensity workload in hack squat
• low dose training
1 x 4 minutes of high intensity workload on treadmill and 2 repetitions x 4 sets of high intensity workload in hack squat

Locations
Country Name City State
Norway Klinikk for rus- og avhengighetsmedisin, St Olavs Hospital Trondheim

Sponsors (2)
Lead Sponsor Collaborator
St. Olavs Hospital Norwegian University of Science and Technology

Country where clinical trial is conducted

Norway, 

Outcome
Type Measure Description Time frame Safety issue
Primary change in oxygen uptake cardiopulmonary exercise test (CPET) objective gas measurements baseline to 8 weeks
Primary change in leg muscular strength One repetition maximum strength test half squat baseline to 8 weeks
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