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Investigating the Efficacy of Caloric Vestibular Stimulation in the Treatment of Substance Use Disorders

Substance Use Disorders Clinical Trial

Official title:
Pilot Investigation of at Home Caloric Vestibular Neuromodulation for Use in Substance Use Disorders

Clinical Trial Summary

The purpose of this study is to determine efficacy and effect of CVS (caloric vestibular stimulation)

Clinical Trial Description

This study is designed as a nonrandomized, single-blind, sham-controlled trail in which willing participants will receive a 5 day course of twice daily caloric vestibular stimulation (CVS) or sham treatment. CVS involves twice daily sessions of CVS each lasting 15 minutes. The week before the intervention baseline characterization of mood and substance craving will be conducted using standard mood and substance use questionnaires. Prior to treatment beginning participants will undergo structural and functional MR imaging. Participants will also undergo a standard battery of questionnaires, including cognitive testing, mood and affect surveys, and surveys specific to SUD. During each of the 5 treatment days the participants will be asked to fill out questionnaires related to mood and craving symptoms. Participants will be blinded to sham stimulation or the standard CVS protocol. At the end of the 5 day course participants will be scanned again in MRI and asked to fill out the same battery of questions. Consistent with the existing standard of care participants will also receive two urine drug screens (UDS) ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03652311
Study type Interventional
Source Wake Forest University Health Sciences
Contact
Status Withdrawn
Phase N/A
Start date November 2019
Completion date January 2020
View Details
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