Substance Use Disorders Clinical Trial
— SMARTOfficial title:
Behavioral Treatment of Adolescent Marijuana Use
Verified date | May 2021 |
Source | Dartmouth-Hitchcock Medical Center |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
This study will continue research designed to improve treatment outcomes for adolescent substance use disorders by integrating neuroscience- and behaviorally-based treatments. In particular, this project will be the first to evaluate whether Working Memory Training can enhance cognitive function and reduce impulsive decision making to improve abstinence outcomes. In addition, an adaptive abstinence-based incentive program will be evaluated as a new method for intervening with those who do not respond to their first-line treatment.
Status | Completed |
Enrollment | 59 |
Est. completion date | August 14, 2018 |
Est. primary completion date | February 2018 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 12 Years to 26 Years |
Eligibility | Inclusion Criteria: Participants must be 12 to 26 years of age, must live at home with the parent who will participate, report using marijuana during the previous 30 days or provide a marijuana-positive urine test, meet criteria for cannabis abuse or dependence, and have a parent who can participate. Exclusion Criteria: DSM criteria for dependence (likely to be adjusted for DSM-5 Use Disorder) on alcohol or other drugs other than marijuana (use of or meeting criteria for abuse of other substances will not be an exclusion criterion), active psychosis, severe medical or psychiatric illness limiting participation, or pregnant or breast-feeding. |
Country | Name | City | State |
---|---|---|---|
United States | Mountain Manor Treatment Center | Baltimore | Maryland |
Lead Sponsor | Collaborator |
---|---|
Dartmouth-Hitchcock Medical Center | Johns Hopkins University, Mountain Manor Treatment Center, National Institute on Drug Abuse (NIDA), Spectrum Youth and Family Services, University of Pennsylvania |
United States,
Stanger C, Scherer EA, Vo HT, Babbin SF, Knapp AA, McKay JR, Budney AJ. Working memory training and high magnitude incentives for youth cannabis use: A SMART pilot trial. Psychol Addict Behav. 2020 Feb;34(1):31-39. doi: 10.1037/adb0000480. Epub 2019 Jun 2 — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Any Cannabis Abstinence | Number of participants with any cannabis abstinence during treatment | Intervention weeks 1 to 14 | |
Primary | Weeks of Continuous Cannabis Abstinence | Weeks of continuous abstinence during treatment | 14 week treatment period | |
Secondary | Any Days of Cannabis Use | Number of participants with any days of cannabis use during treatment | Intervention weeks 1 to 14 | |
Secondary | Days of Cannabis Use | Percent of Days Used During the Treatment Period | The intervention period between Week 1 and Week 14 | |
Secondary | Any Cannabis Abstinence Across Four Treatment Strategies | Number of participants who achieved at least one week of abstinence | Treatment period between week 1 and week 14 | |
Secondary | Weeks of Cannabis Abstinence Across Four Treatment Strategies | Mean weeks of continuous cannabis abstinence among those who achieved at least one week of abstinence | Treatment period between week 1 and week 14 |
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