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A Laboratory Model for Heroin Abuse Medications - 8

Substance-Related Disorders Clinical Trial

Official title:
A Laboratory Model for Heroin Abuse Medications

Clinical Trial Summary

The purpose of this study is to evaluate the effects of treatment medications (methadone, buprenorphine, LAAM, naltrexone, naltrexone microcapsules, and methoclocinnamox) on I.V. and smoked heroin self-administration."

Clinical Trial Description

Abuse of prescription opioid medications has increased dramatically in the U.S. during the past decade, as indicated by a variety of epidemiological sources. However, few studies have systematically examined the relative reinforcing effects of commonly abused opioid medications. The current inpatient study was designed to compare the effects of intravenously delivered fentanyl , oxycodone, morphine, buprenorphine and heroin in morphine-maintained heroin abusers. All of the participants received all of the drugs tested; drugs and doses were administered in non-systematic order. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00000273
Study type Interventional
Source New York State Psychiatric Institute
Contact
Status Completed
Phase Phase 2
Start date August 1995
Completion date November 2005
View Details
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