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Clinical Trial Details — Status: Active, not recruiting

Administrative data

NCT number NCT02408952
Other study ID # 11-07796
Secondary ID
Status Active, not recruiting
Phase N/A
First received
Last updated
Start date October 2011
Est. completion date December 31, 2025

Study information

Verified date July 2023
Source Kaiser Permanente
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

This study evaluates the implementation and effectiveness of two modalities of Screening, Brief Intervention and Referral to Treatment (SBIRT) to reduce adolescent alcohol and other drug (AOD) use in a large pediatrics clinic.


Description:

Health systems have not implemented Screening, Brief Intervention and Referral to Treatment (SBIRT) for adolescents despite research demonstrating its effectiveness. Based on prior research that identified barriers to AOD screening for adolescents in pediatric Primary Care (PC) and a pilot study that found SBIRT was feasible, well-received and promoted referrals to and initiation of specialty treatment, the current research application proposes to randomize 45 Primary Care Physicians (PCPs) in the pediatrics clinic of a medical center within a large, managed care health system, Kaiser Permanente Northern California, to three arms - 1) Usual Care; 2) SBIRT delivered by PCPs; and 3) SBIRT delivered by Behavioral Medicine Specialists (BMS). The study objective is to compare the implementation, effectiveness and cost-effectiveness of SBIRT for adolescents in PC in the three study arms. Patients will complete evidence-based screening and AOD assessment measures which have been embedded in the health plan's electronic medical record (EMR). A mixed model will be used to compare implementation outcomes (rates of screening and identification, brief intervention, referral to Chemical Dependency treatment and treatment initiation), and effectiveness (patient outcomes of AOD use and abstinence) at 12 months. The model accounts for the intra-class correlations across patients within providers. Cost-effectiveness relative to implementation and patient outcomes will be examined. Barriers and facilitators of implementation, and feasibility via qualitative interviews with clinicians and administrators will be examined as well. The study is significant in that it examines issues that must be addressed to spur widespread adaptation of SBIRT. The proposed interventions are highly feasible in the current environment of health reform due to increased resources and training to Federally Qualified Health Centers and private health plans. It is innovative in using the EMR to change clinical practice and systematically integrate AOD in PC, and as a platform for collecting research data.


Recruitment information / eligibility

Status Active, not recruiting
Enrollment 9084
Est. completion date December 31, 2025
Est. primary completion date October 2013
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 12 Years to 80 Years
Eligibility There are two study populations as described below thus the large age limit range. Inclusion Criteria: - All adolescent primary care providers at the pediatric primary care clinic will be included. - All adolescent patient electronic records, ages 12-18, at the pediatric primary care will be examined. Exclusion Criteria: - Any adolescent primary care providers not practicing at the pediatric primary care clinic research site will be excluded. - Adolescents electronic records who are not part of the research site pediatric clinic will be excluded.

Study Design


Intervention

Behavioral:
Primary Care Physician
The screening, brief intervention and referral to treatment is delivered by the Primary Care Physician
Behavioral Medicine Specialist
The screening, brief intervention and referral to treatment is delivered by the Behavioral Medicine Specialist.

Locations

Country Name City State
United States Stacy A Sterling Oakland California

Sponsors (1)

Lead Sponsor Collaborator
Kaiser Permanente

Country where clinical trial is conducted

United States, 

References & Publications (160)

Alexandre PK, French MT, Matzger H, Weisner C. Addiction treatment history, medical services utilization, and cost: a longitudinal analysis of problem drinkers. J Addict Dis. 2006;25(1):105-20. doi: 10.1300/J069v25n01_13. — View Citation

American Academy of Pediatrics. Committee on Substance Abuse. American Academy of Pediatrics. Committee on Substance Abuse. Tobacco, alcohol, and other drugs: the role of the pediatrician in prevention and management of substance abuse. Pediatrics. 1998 Jan;101(1 Pt 1):125-8. — View Citation

American Academy of Pediatrics. Periodic survey of fellows: 45% of Fellows routinely screen for alcohol use., 2002. http://aapnews.aappublications.org/cgi/content/short/14/10/1. Accessed April 6, 2009

Ammon L, Lu Y, Weisner C. Adolescents in substance abuse treatment: Are they at risk for HIV? 131st meeting of American Public Health Association, San Francisco, CA, 2003

Ammon L, Sterling S, Mertens J, Weisner C. Adolescents in private chemical dependency programs: who are most at risk for HIV? J Subst Abuse Treat. 2005 Jul;29(1):39-45. doi: 10.1016/j.jsat.2005.03.003. — View Citation

Aspy CB, Mold JW, Thompson DM, Blondell RD, Landers PS, Reilly KE, Wright-Eakers L. Integrating screening and interventions for unhealthy behaviors into primary care practices. Am J Prev Med. 2008 Nov;35(5 Suppl):S373-80. doi: 10.1016/j.amepre.2008.08.015. — View Citation

Babor TE, Higgins-Biddle J, Dauser D, Higgins P, Burleson JA. Alcohol screening and brief intervention in primary care settings: implementation models and predictors. J Stud Alcohol. 2005 May;66(3):361-8. doi: 10.15288/jsa.2005.66.361. — View Citation

Babor TF, Higgins-Biddle JC, Dauser D, Burleson JA, Zarkin GA, Bray J. Brief interventions for at-risk drinking: patient outcomes and cost-effectiveness in managed care organizations. Alcohol Alcohol. 2006 Nov-Dec;41(6):624-31. doi: 10.1093/alcalc/agl078. Epub 2006 Oct 10. — View Citation

Baer JS, Kivlahan DR, Blume AW, McKnight P, Marlatt GA. Brief intervention for heavy-drinking college students: 4-year follow-up and natural history. Am J Public Health. 2001 Aug;91(8):1310-6. doi: 10.2105/ajph.91.8.1310. — View Citation

Balsa AI, Homer JF, French MT, Weisner CM. Substance use, education, employment, and criminal activity outcomes of adolescents in outpatient chemical dependency programs. J Behav Health Serv Res. 2009 Jan;36(1):75-95. doi: 10.1007/s11414-007-9095-x. Epub 2007 Dec 7. — View Citation

Barnett NP, Monti PM, Cherpitel C, Bendtsen P, Borges G, Colby SM, Nordqvist C, Johansson K. Identification and brief treatment of alcohol problems with medical patients: an international perspective. Alcohol Clin Exp Res. 2003 Feb;27(2):262-70. doi: 10.1097/01.ALC.0000057123.36127.8B. — View Citation

Barnett NP, Monti PM, Wood MD. Motivational interviewing for alcohol-involved adolescents in the emergency room. . In: Wagner EF, Waldron HB, eds. Innovations in Adolescent Substance Abuse Interventions. Amsterdam, Netherlands: Pergamon/Elsevier Science Inc, 2001:143-168

Barrientos-Gutierrez T, Gimeno D, Mangione TW, Harrist RB, Amick BC. Drinking social norms and drinking behaviours: a multilevel analysis of 137 workgroups in 16 worksites. Occup Environ Med. 2007 Sep;64(9):602-8. doi: 10.1136/oem.2006.031765. Epub 2007 May 24. — View Citation

Barroso T, Castanhola R, Marta M, et al. Effectiveness of brief alcohol interventions by clinical nurse specialists (CNS) in primary care settings. 2010 ISBRA World Congress, Paris, France, Sep 13-16, 2010

Barry KL, Blow FC, Willenbring ML, McCormick R, Brockmann LM, Visnic S. Use of Alcohol Screening and Brief Interventions<br />in Primary Care Settings:Implementation and Barriers. Subst Abus. 2004 Mar;25(1):27-36. doi: 10.1300/J465v25n01_05. — View Citation

Bava S, Tapert SF. Adolescent brain development and the risk for alcohol and other drug problems. Neuropsychol Rev. 2010 Dec;20(4):398-413. doi: 10.1007/s11065-010-9146-6. Epub 2010 Oct 19. — View Citation

Bertholet N, Daeppen JB, Wietlisbach V, Fleming M, Burnand B. Reduction of alcohol consumption by brief alcohol intervention in primary care: systematic review and meta-analysis. Arch Intern Med. 2005 May 9;165(9):986-95. doi: 10.1001/archinte.165.9.986. — View Citation

Bethell C, Klein J, Peck C. Assessing health system provision of adolescent preventive services: the Young Adult Health Care Survey. Med Care. 2001 May;39(5):478-90. doi: 10.1097/00005650-200105000-00008. — View Citation

Bien TH, Miller WR, Tonigan JS. Brief interventions for alcohol problems: a review. Addiction. 1993 Mar;88(3):315-35. doi: 10.1111/j.1360-0443.1993.tb00820.x. — View Citation

Blum R. Physicians' assessment of deficiencies and desire for training in adolescent care. J Med Educ. 1987 May;62(5):401-7. doi: 10.1097/00001888-198705000-00005. — View Citation

Borsari B, Carey KB. Effects of a brief motivational intervention with college student drinkers. J Consult Clin Psychol. 2000 Aug;68(4):728-33. — View Citation

Brindis C, Park MJ, Ozer EM, Irwin CE Jr. Adolescents' access to health services and clinical preventive health care: crossing the great divide. Pediatr Ann. 2002 Sep;31(9):575-81. doi: 10.3928/0090-4481-20020901-10. No abstract available. — View Citation

Brown JD, Wissow LS. Discussion of sensitive health topics with youth during primary care visits: relationship to youth perceptions of care. J Adolesc Health. 2009 Jan;44(1):48-54. doi: 10.1016/j.jadohealth.2008.06.018. Epub 2008 Oct 25. — View Citation

Brown SA, Tapert SF, Granholm E, Delis DC. Neurocognitive functioning of adolescents: effects of protracted alcohol use. Alcohol Clin Exp Res. 2000 Feb;24(2):164-71. — View Citation

Bryk AS, Raudenbush SW. Hierarchical Linear Models: Applications and Data Analysis Methods. Newbury Park: Sage, 1992

Burke PJ, Da Silva JD, Vaughan BL, Knight JR. Training high school counselors on the use of motivational interviewing to screen for substance abuse. Subst Abus. 2005 Dec;26(3-4):31-4. doi: 10.1300/j465v26n03_07. — View Citation

Cabana MD, Rand CS, Powe NR, Wu AW, Wilson MH, Abboud PA, Rubin HR. Why don't physicians follow clinical practice guidelines? A framework for improvement. JAMA. 1999 Oct 20;282(15):1458-65. doi: 10.1001/jama.282.15.1458. — View Citation

Campbell CI, Chi F, Sterling S, Kohn C, Weisner C. Self-initiated tobacco cessation and substance use outcomes among adolescents entering substance use treatment in a managed care organization. Addict Behav. 2009 Feb;34(2):171-9. doi: 10.1016/j.addbeh.2008.10.002. Epub 2008 Oct 10. — View Citation

Carey KB, Correia CJ. Drinking motives predict alcohol-related problems in college students. J Stud Alcohol. 1997 Jan;58(1):100-5. doi: 10.15288/jsa.1997.58.100. — View Citation

Chambers RA, Taylor JR, Potenza MN. Developmental neurocircuitry of motivation in adolescence: a critical period of addiction vulnerability. Am J Psychiatry. 2003 Jun;160(6):1041-52. doi: 10.1176/appi.ajp.160.6.1041. — View Citation

Chi FW, Sterling S, Campbell CI, et al. Twelve-step participation at 5-year follow-up among a diverse sample of adolescents entering chemical dependency treatment. Joint Meeting on Adolescent Treatment Effectiveness (JMATE), Washington, DC, Mar 25-27, 2008

Chi FW, Sterling S, Weisner C. Adolescents with co-occurring substance use and mental conditions in a private managed care health plan: prevalence, patient characteristics, and treatment initiation and engagement. Am J Addict. 2006;15 Suppl 1:67-79. doi: 10.1080/10550490601006022. — View Citation

Chi FW, Weisner CM. Nine-year psychiatric trajectories and substance use outcomes: an application of the group-based modeling approach. Eval Rev. 2008 Feb;32(1):39-58. doi: 10.1177/0193841X07307317. — View Citation

Clark DB, Gordon AJ, Ettaro LR, Owens JM, Moss HB. Screening and brief intervention for underage drinkers. Mayo Clin Proc. 2010 Apr;85(4):380-91. doi: 10.4065/mcp.2008.0638. — View Citation

Cohen J. Statistical Power Analysis for the Behavioral Sciences. Hillsdale, NJ: Lawrence Erlbaum Associates, Inc., 1988

Cosby RH, Howard M, Kaczorowski J, Willan AR, Sellors JW. Randomizing patients by family practice: sample size estimation, intracluster correlation and data analysis. Fam Pract. 2003 Feb;20(1):77-82. doi: 10.1093/fampra/20.1.77. — View Citation

Cowell AJ, Bray JW, Mills MJ, Hinde JM. Conducting economic evaluations of screening and brief intervention for hazardous drinking: Methods and evidence to date for informing policy. Drug Alcohol Rev. 2010 Nov;29(6):623-30. doi: 10.1111/j.1465-3362.2010.00238.x. — View Citation

Curley B. Healthcare reform law gives big boost to addiction treatment and prevention. Join Together. Apr 9, 2010. http://www.jointogether.org/news/features/2010/healthcare-reform-law-gives.html. Accessed Oct 21, 2010

D'Amico EJ, Miles JN, Stern SA, Meredith LS. Brief motivational interviewing for teens at risk of substance use consequences: a randomized pilot study in a primary care clinic. J Subst Abuse Treat. 2008 Jul;35(1):53-61. doi: 10.1016/j.jsat.2007.08.008. Epub 2007 Nov 26. — View Citation

D'Onofrio G, Degutis LC. Preventive care in the emergency department: screening and brief intervention for alcohol problems in the emergency department: a systematic review. Acad Emerg Med. 2002 Jun;9(6):627-38. doi: 10.1111/j.1553-2712.2002.tb02304.x. — View Citation

de Leeuw J, Kreft IG. Questioning multilevel models. J Educ Behav Stat. 1995;20 (2):171-189

Desy PM, Perhats C. Alcohol screening, brief intervention, and referral in the emergency department: an implementation study. J Emerg Nurs. 2008 Feb;34(1):11-9. doi: 10.1016/j.jen.2007.03.019. Epub 2007 Dec 3. — View Citation

Di Forti M, Morrison PD, Butt A, Murray RM. Cannabis use and psychiatric and cogitive disorders: the chicken or the egg? Curr Opin Psychiatry. 2007 May;20(3):228-34. doi: 10.1097/YCO.0b013e3280fa838e. — View Citation

Ellen JM, Franzgrote M, Irwin CE Jr, Millstein SG. Primary care physicians' screening of adolescent patients: a survey of California physicians. J Adolesc Health. 1998 Jun;22(6):433-8. doi: 10.1016/s1054-139x(97)00276-0. — View Citation

Elster A. The American Medical Association Guidelines for Adolescent Preventive Services. Arch Pediatr Adolesc Med. 1997 Sep;151(9):958-9. doi: 10.1001/archpedi.1997.02170460096021. No abstract available. — View Citation

Emans SJ, Bravender T, Knight J, Frazer C, Luoni M, Berkowitz C, Armstrong E, Goodman E. Adolescent medicine training in pediatric residency programs: are we doing a good job? Pediatrics. 1998 Sep;102(3 Pt 1):588-95. doi: 10.1542/peds.102.3.588. — View Citation

Ewing GB, Selassie AW, Lopez CH, McCutcheon EP. Self-report of delivery of clinical preventive services by U.S. physicians. Comparing specialty, gender, age, setting of practice, and area of practice. Am J Prev Med. 1999 Jul;17(1):62-72. doi: 10.1016/s0749-3797(99)00032-x. — View Citation

Fleming MF. Strategies to increase alcohol screening in health care settings. Alcohol Health Res World. 1997;21(4):340-7. — View Citation

Franzgrote M, Ellen JM, Millstein SG, Irwin CE Jr. Screening for adolescent smoking among primary care physicians in California. Am J Public Health. 1997 Aug;87(8):1341-5. doi: 10.2105/ajph.87.8.1341. — View Citation

Fraser D. The depression initiative: an alliance to improve treatment. The Permanente Journal. 1998;2 (3):5-11

Friedman LS, Johnson B, Brett AS. Evaluation of substance-abusing adolescents by primary care physicians. J Adolesc Health Care. 1990 May;11(3):227-30. doi: 10.1016/0197-0070(90)90353-4. — View Citation

Friedmann PD, McCullough D, Chin MH, Saitz R. Screening and intervention for alcohol problems. A national survey of primary care physicians and psychiatrists. J Gen Intern Med. 2000 Feb;15(2):84-91. doi: 10.1046/j.1525-1497.2000.03379.x. — View Citation

Friedmann PD, McCullough D, Saitz R. Screening and intervention for illicit drug abuse: a national survey of primary care physicians and psychiatrists. Arch Intern Med. 2001 Jan 22;161(2):248-51. doi: 10.1001/archinte.161.2.248. — View Citation

Gardner W, Kelleher KJ, Pajer KA, Campo JV. Primary care clinicians' use of standardized tools to assess child psychosocial problems. Ambul Pediatr. 2003 Jul-Aug;3(4):191-5. doi: 10.1367/1539-4409(2003)0032.0.co;2. — View Citation

Gardner W, Pajer KA, Kelleher KJ, Scholle SH, Wasserman RC. Child sex differences in primary care clinicians' mental health care of children and adolescents. Arch Pediatr Adolesc Med. 2002 May;156(5):454-9. doi: 10.1001/archpedi.156.5.454. — View Citation

Gates S, McCambridge J, Smith LA, Foxcroft DR. Interventions for prevention of drug use by young people delivered in non-school settings. Cochrane Database Syst Rev. 2006 Jan 25;(1):CD005030. doi: 10.1002/14651858.CD005030.pub2. — View Citation

Gil AG, Wagner EF, Tubman JG. Culturally sensitive substance abuse intervention for Hispanic and African American adolescents: empirical examples from the Alcohol Treatment Targeting Adolescents in Need (ATTAIN) Project. Addiction. 2004 Nov;99 Suppl 2:140-50. doi: 10.1111/j.1360-0443.2004.00861.x. — View Citation

Goodall CA, Ayoub AF, Crawford A, Smith I, Bowman A, Koppel D, Gilchrist G. Nurse-delivered brief interventions for hazardous drinkers with alcohol-related facial trauma: a prospective randomised controlled trial. Br J Oral Maxillofac Surg. 2008 Mar;46(2):96-101. doi: 10.1016/j.bjoms.2007.11.014. Epub 2007 Dec 21. — View Citation

Gottlieb NH, Mullen PD, McAlister AL. Patients' substance abuse and the primary care physician: patterns of practice. Addict Behav. 1987;12(1):23-32. doi: 10.1016/0306-4603(87)90005-0. — View Citation

Grenard JL, Ames SL, Wiers RW, Thush C, Stacy AW, Sussman S. Brief intervention for substance use among at-risk adolescents: a pilot study. J Adolesc Health. 2007 Feb;40(2):188-91. doi: 10.1016/j.jadohealth.2006.08.008. Epub 2006 Oct 27. — View Citation

Guide to Clinical Preventive Services 2010 - 2011. AHRQ Publication No. 10-05145: Agency for Healthcare Research and Quality, 2010. http://www.ahrq.gov/clinic/pocketgd.htm. Accessed Oct 25, 2010

Hsiao C. Analysis of Panel Data. New York: Cambridge University Press, 1986

Hunkeler EM, Meresman JF, Hargreaves WA, Fireman B, Berman WH, Kirsch AJ, Groebe J, Hurt SW, Braden P, Getzell M, Feigenbaum PA, Peng T, Salzer M. Efficacy of nurse telehealth care and peer support in augmenting treatment of depression in primary care. Arch Fam Med. 2000 Aug;9(8):700-8. doi: 10.1001/archfami.9.8.700. — View Citation

Indications for management and referral of patients involved in substance abuse. American Academy of Pediatrics. Committee on Substance Abuse. Pediatrics. 2000 Jul;106(1 Pt 1):143-8. doi: 10.1542/peds.106.1.143. — View Citation

Institute of Medicine (US) Committee on Crossing the Quality Chasm: Adaptation to Mental Health and Addictive Disorders. Improving the Quality of Health Care for Mental and Substance-Use Conditions: Quality Chasm Series. Washington (DC): National Academies Press (US); 2006. Available from http://www.ncbi.nlm.nih.gov/books/NBK19830/ — View Citation

Institute of Medicine (US) Committee on Quality of Health Care in America. Crossing the Quality Chasm: A New Health System for the 21st Century. Washington (DC): National Academies Press (US); 2001. Available from http://www.ncbi.nlm.nih.gov/books/NBK222274/ — View Citation

Johnston LD, O'Malley PM, Bachman JG, et al. Cigarette smoking among American teens continues to decline, but more slowly than in the past [press release]. Ann Arbor, MI: University of Michigan News and Information Services, 2006. http://www.monitoringthefuture.org/pressreleases/06cigpr.pdf. Accessed Oct 20, 2010

Johnston LD, O'Malley PM, Bachman JG, et al. Monitoring the Future national results on adolescent drug use: Overview of key findings 2004. Bethesda, MD: National Institute on Drug Abuse, 2005. http://www.drugabuse.gov/PDF/overview2004.pdf. Accessed Oct 19, 2009

Kaner E, Bland M, Cassidy P, et al. Screening and brief alcohol intervention in routine primary care In the UK: SIPS trial outcomes at six months. 2010 ISBRA World Congress, Paris, France, Sep 13-16, 2010

Kanouse DE, Kallich JD, Kahan JP. Dissemination of effectiveness and outcomes research. Health Policy. 1995 Dec;34(3):167-92. doi: 10.1016/0168-8510(95)00760-1. — View Citation

Kaplan JE, Benson C, Holmes KK, Brooks JT, Pau A, Masur H; Centers for Disease Control and Prevention (CDC); National Institutes of Health; HIV Medicine Association of the Infectious Diseases Society of America. Guidelines for prevention and treatment of opportunistic infections in HIV-infected adults and adolescents: recommendations from CDC, the National Institutes of Health, and the HIV Medicine Association of the Infectious Diseases Society of America. MMWR Recomm Rep. 2009 Apr 10;58(RR-4):1-207; quiz CE1-4. — View Citation

Kaul P, Coupey SM. Clinical evaluation of substance abuse. Pediatr Rev. 2002 Mar;23(3):85-94. doi: 10.1542/pir.23-3-85. No abstract available. — View Citation

Killip S, Mahfoud Z, Pearce K. What is an intracluster correlation coefficient? Crucial concepts for primary care researchers. Ann Fam Med. 2004 May-Jun;2(3):204-8. doi: 10.1370/afm.141. — View Citation

Klein JD, Wilson KM. Delivering quality care: adolescents' discussion of health risks with their providers. J Adolesc Health. 2002 Mar;30(3):190-5. doi: 10.1016/s1054-139x(01)00342-1. — View Citation

Knight JR, Harris SK, Sherritt L, Van Hook S, Lawrence N, Brooks T, Carey P, Kossack R, Kulig J. Prevalence of positive substance abuse screen results among adolescent primary care patients. Arch Pediatr Adolesc Med. 2007 Nov;161(11):1035-41. doi: 10.1001/archpedi.161.11.1035. — View Citation

Knight JR, Sherritt L, Harris SK, Gates EC, Chang G. Validity of brief alcohol screening tests among adolescents: a comparison of the AUDIT, POSIT, CAGE, and CRAFFT. Alcohol Clin Exp Res. 2003 Jan;27(1):67-73. doi: 10.1097/01.ALC.0000046598.59317.3A. — View Citation

Knight JR, Sherritt L, Shrier LA, Harris SK, Chang G. Validity of the CRAFFT substance abuse screening test among adolescent clinic patients. Arch Pediatr Adolesc Med. 2002 Jun;156(6):607-14. doi: 10.1001/archpedi.156.6.607. — View Citation

Knight JR, Sherritt L, Van Hook S, Gates EC, Levy S, Chang G. Motivational interviewing for adolescent substance use: a pilot study. J Adolesc Health. 2005 Aug;37(2):167-9. doi: 10.1016/j.jadohealth.2004.08.020. — View Citation

Knight JR. The role of the primary care provider in preventing and treating alcohol problems in adolescents. Ambul Pediatr. 2001 May-Jun;1(3):150-61. doi: 10.1367/1539-4409(2001)0012.0.co;2. — View Citation

Larimer ME, Turner AP, Anderson BK, Fader JS, Kilmer JR, Palmer RS, Cronce JM. Evaluating a brief alcohol intervention with fraternities. J Stud Alcohol. 2001 May;62(3):370-80. doi: 10.15288/jsa.2001.62.370. — View Citation

Lawendowski LA. A motivational intervention for adolescent smokers. Prev Med. 1998 Sep-Oct;27(5 Pt 3):A39-46. doi: 10.1006/pmed.1998.0424. — View Citation

Leffingwell TR. Motivational Interviewing Knowledge and Attitudes Test (MIKAT) for evaluation of training outcomes. Minuet. 2006;13 (1):10-11

Leontieva L, Horn K, Haque A, Helmkamp J, Ehrlich P, Williams J. Readiness to change problematic drinking assessed in the emergency department as a predictor of change. J Crit Care. 2005 Sep;20(3):251-6. doi: 10.1016/j.jcrc.2005.05.009. — View Citation

Levy S, Vaughan BL, Knight JR. Office-based intervention for adolescent substance abuse. Pediatr Clin North Am. 2002 Apr;49(2):329-43. doi: 10.1016/s0031-3955(01)00007-4. — View Citation

Marlatt GA, Baer JS, Kivlahan DR, Dimeff LA, Larimer ME, Quigley LA, Somers JM, Williams E. Screening and brief intervention for high-risk college student drinkers: results from a 2-year follow-up assessment. J Consult Clin Psychol. 1998 Aug;66(4):604-15. doi: 10.1037//0022-006x.66.4.604. — View Citation

Martin G, Copeland J, Swift W. The Adolescent Cannabis Check-Up: feasibility of a brief intervention for young cannabis users. J Subst Abuse Treat. 2005 Oct;29(3):207-13. doi: 10.1016/j.jsat.2005.06.005. — View Citation

Massachusetts Department of Public Health Bureau of Substance Abuse Services. Provider Guide: Adolescent Screening, Brief Intervention, and Referral to Treatment Using the CRAFFT Screening Tool. Boston: Massachusetts Department of Public Health, 2009

McCambridge J, Strang J. The efficacy of single-session motivational interviewing in reducing drug consumption and perceptions of drug-related risk and harm among young people: results from a multi-site cluster randomized trial. Addiction. 2004 Jan;99(1):39-52. doi: 10.1111/j.1360-0443.2004.00564.x. — View Citation

McCrady BS, Richter SS, Morgan TJ, Slade J, Pfeifer C. Involving health care workers in screening for alcohol problems. J Addict Dis. 1996;15(3):45-58. doi: 10.1300/J069v15n03_03. — View Citation

McIntosh MC, Leigh G, Baldwin NJ, Marmulak J. Reducing alcohol consumption. Comparing three brief methods in family practice. Can Fam Physician. 1997 Nov;43:1959-62, 1965-7. — View Citation

Mental Health America. Parity and health care reform: important changes for behavioral health, 2010. http://www.mentalhealthamerica.net/go/action/policy-issues-a-z/healthcare-reform. Accessed Oct 21, 2010

Merenstein D, Green L, Fryer GE, Dovey S. Shortchanging adolescents: room for improvement in preventive care by physicians. Fam Med. 2001 Feb;33(2):120-3. — View Citation

Meresman JF, Hunkeler EM, Hargreaves WA, Kirsch AJ, Robinson P, Green A, Mann EZ, Getzell M, Feigenbaum P. A case report: implementing a nurse telecare program for treating depression in primary care. Psychiatr Q. 2003 Spring;74(1):61-73. doi: 10.1023/a:1021145722959. — View Citation

Mertens JR, Flisher AJ, Fleming MF, Weisner CM. Medical conditions of adolescents in alcohol and drug treatment: comparison with matched controls. J Adolesc Health. 2007 Feb;40(2):173-9. doi: 10.1016/j.jadohealth.2006.09.021. Epub 2006 Nov 29. — View Citation

Mertens JR, Flisher AJ, Satre DD, Weisner CM. The role of medical conditions and primary care services in 5-year substance use outcomes among chemical dependency treatment patients. Drug Alcohol Depend. 2008 Nov 1;98(1-2):45-53. doi: 10.1016/j.drugalcdep.2008.04.007. Epub 2008 Jun 20. — View Citation

Mertens JR, Lu YW, Parthasarathy S, Moore C, Weisner CM. Medical and psychiatric conditions of alcohol and drug treatment patients in an HMO: comparison with matched controls. Arch Intern Med. 2003 Nov 10;163(20):2511-7. doi: 10.1001/archinte.163.20.2511. — View Citation

Mertens JR, Weisner C, Ray GT, Fireman B, Walsh K. Hazardous drinkers and drug users in HMO primary care: prevalence, medical conditions, and costs. Alcohol Clin Exp Res. 2005 Jun;29(6):989-98. doi: 10.1097/01.alc.0000167958.68586.3d. — View Citation

Mertens JR, Weisner CM. Predictors of substance abuse treatment retention among women and men in an HMO. Alcohol Clin Exp Res. 2000 Oct;24(10):1525-33. — View Citation

Meyers K, McLellan AT, Jaeger JL, Pettinati HM. The development of the Comprehensive Addiction Severity Index for Adolescents (CASI-A). An interview for assessing multiple problems of adolescents. J Subst Abuse Treat. 1995 May-Jun;12(3):181-93. doi: 10.1016/0740-5472(95)00009-t. — View Citation

Miller NS, Sheppard LM, Colenda CC, Magen J. Why physicians are unprepared to treat patients who have alcohol- and drug-related disorders. Acad Med. 2001 May;76(5):410-8. doi: 10.1097/00001888-200105000-00007. — View Citation

Miller WR, Rollnick S. Motivational Interviewing: Preparing People for Change. 2nd ed. New York: Guilford Press, 2002

Monti PM, Colby SM, Barnett NP, Spirito A, Rohsenow DJ, Myers M, Woolard R, Lewander W. Brief intervention for harm reduction with alcohol-positive older adolescents in a hospital emergency department. J Consult Clin Psychol. 1999 Dec;67(6):989-94. doi: 10.1037//0022-006x.67.6.989. — View Citation

Moyers TB, Martin T, Manuel JK, Hendrickson SM, Miller WR. Assessing competence in the use of motivational interviewing. J Subst Abuse Treat. 2005 Jan;28(1):19-26. doi: 10.1016/j.jsat.2004.11.001. — View Citation

Murphy JG, Duchnick JJ, Vuchinich RE, Davison JW, Karg RS, Olson AM, Smith AF, Coffey TT. Relative efficacy of a brief motivational intervention for college student drinkers. Psychol Addict Behav. 2001 Dec;15(4):373-9. doi: 10.1037//0893-164x.15.4.373. — View Citation

Muthén B, Kaplan D, Hollis M. On structural equation modeling with data that are not missing completely at random. Psychometrika. 1987;42:431-462

National Institute on Alcohol Abuse and Alcoholism. Five-year strategic plan (FY07-11): Alcohol across the lifespan. Washington, DC: U.S. Department of Health and Human Services, 2006. http://pubs.niaaa.nih.gov/publications/StrategicPlan/NIAAASTRATEGICPLAN.htm. Accessed Oct 18, 2010.

National Institute on Alcohol Abuse and Alcoholism. Statistical snapshot of underage drinking, 2008. http://www.niaaa.nih.gov/AboutNIAAA/NIAAASponsoredPrograms/StatisticalSnapshotUnderageDrinking.htm. Accessed Oct 19, 2010

Ockene JK, Adams A, Hurley TG, Wheeler EV, Hebert JR. Brief physician- and nurse practitioner-delivered counseling for high-risk drinkers: does it work? Arch Intern Med. 1999 Oct 11;159(18):2198-205. doi: 10.1001/archinte.159.18.2198. — View Citation

Office of National Drug Control Policy. The economic costs of drug abuse in the United States, 1992-2002. Washington, DC: Executive Office of the President (Publication No. 207303), 2004

Ogborne AC, Rush B, Ekdahl A, Fondacaro R. The views of health and social service professionals regarding alcohol problems and their treatment. Int J Addict. 1986 Sep-Oct;21(9-10):1051-8. doi: 10.3109/10826088609077254. — View Citation

Ozer EM, Adams SH, Gardner LR, Mailloux DE, Wibbelsman CJ, Irwin CE Jr. Provider self-efficacy and the screening of adolescents for risky health behaviors. J Adolesc Health. 2004 Aug;35(2):101-7. doi: 10.1016/j.jadohealth.2003.09.016. — View Citation

Ozer EM, Adams SH, Lustig JL, Millstein SG, Camfield K, El-Diwany S, Volpe S, Irwin CE Jr. Can it be done? Implementing adolescent clinical preventive services. Health Serv Res. 2001 Dec;36(6 Pt 2):150-65. — View Citation

Parthasarathy S, Mertens J, Moore C, Weisner C. Utilization and cost impact of integrating substance abuse treatment and primary care. Med Care. 2003 Mar;41(3):357-67. doi: 10.1097/01.MLR.0000053018.20700.56. — View Citation

Parthasarathy S, Weisner C, Hu TW, Moore C. Association of outpatient alcohol and drug treatment with health care utilization and cost: revisiting the offset hypothesis. J Stud Alcohol. 2001 Jan;62(1):89-97. doi: 10.15288/jsa.2001.62.89. — View Citation

Parthasarathy S, Weisner C. Health care services use by adolescents with intakes into an outpatient alcohol and drug treatment program. Am J Addict. 2006;15 Suppl 1:113-21. doi: 10.1080/10550490601006097. — View Citation

Parthasarathy S, Weisner CM. Five-year trajectories of health care utilization and cost in a drug and alcohol treatment sample. Drug Alcohol Depend. 2005 Nov 1;80(2):231-40. doi: 10.1016/j.drugalcdep.2005.04.004. — View Citation

Peterson PL, Baer JS, Wells EA, Ginzler JA, Garrett SB. Short-term effects of a brief motivational intervention to reduce alcohol and drug risk among homeless adolescents. Psychol Addict Behav. 2006 Sep;20(3):254-64. doi: 10.1037/0893-164X.20.3.254. — View Citation

Phillips JL, Smithstan P. Brief intervention: An approach for substance abusing adolescents. Trainer and trainee guide. A CARS training program prepared by Joel L. Phillips and Pam Smithstan, MFT, based on the work of Ken Winters, PhD. Santa Rosa, CA: Center for Applied Research Solutions, 2006. http://indianeducation.org/userfiles/file/Session%207_3b%20Brief%20Intervention%20FBecker.pdf

Qualitative Solutions and Research: QSR NUD*IST [computer program]. 5.0. Thousand Oaks, CA: Sage Publications; 2000

Reiff-Hekking S, Ockene JK, Hurley TG, Reed GW. Brief physician and nurse practitioner-delivered counseling for high-risk drinking. Results at 12-month follow-up. J Gen Intern Med. 2005 Jan;20(1):7-13. doi: 10.1111/j.1525-1497.2005.21240.x. — View Citation

Saitz R, Friedmann PD, Sullivan LM, Winter MR, Lloyd-Travaglini C, Moskowitz MA, Samet JH. Professional satisfaction experienced when caring for substance-abusing patients: faculty and resident physician perspectives. J Gen Intern Med. 2002 May;17(5):373-6. doi: 10.1046/j.1525-1497.2002.10520.x. — View Citation

Saitz R, Svikis D, D'Onofrio G, Kraemer KL, Perl H. Challenges applying alcohol brief intervention in diverse practice settings: populations, outcomes, and costs. Alcohol Clin Exp Res. 2006 Feb;30(2):332-8. doi: 10.1111/j.1530-0277.2006.00038.x. — View Citation

Saunders KW, Davis RL, Stergachis A. Group Health Cooperative. In: Strom BL, ed. Pharmacoepidemiology. 4th ed. New York: Wiley, 2005:223-239

Schmittdiel JA, Shortell SM, Rundall TG, Bodenheimer T, Selby JV. Effect of primary health care orientation on chronic care management. Ann Fam Med. 2006 Mar-Apr;4(2):117-23. doi: 10.1370/afm.520. — View Citation

Scott M, Parthasarathy S, Kohn C, Hinman A, Sterling S, Weisner C. Adolescents with substance diagnoses in an HMO: factors associated with medical provider referrals to substance abuse and mental health treatment. Ment Health Serv Res. 2004 Mar;6(1):47-60. doi: 10.1023/b:mhsr.0000011256.70502.ed. — View Citation

Selby JV, Smith DH, Johnson ES, et al. Kaiser Permanente Medical Care Program. In: Strom BL, ed. Pharmacoepidemiology. 4th ed. New York: Wiley, 2005:241-259

Selby JV, Uratsu CS, Fireman B, Schmittdiel JA, Peng T, Rodondi N, Karter AJ, Kerr EA. Treatment intensification and risk factor control: toward more clinically relevant quality measures. Med Care. 2009 Apr;47(4):395-402. doi: 10.1097/mlr.0b013e31818d775c. — View Citation

Shrier LA, Harris SK, Kurland M, Knight JR. Substance use problems and associated psychiatric symptoms among adolescents in primary care. Pediatrics. 2003 Jun;111(6 Pt 1):e699-705. doi: 10.1542/peds.111.6.e699. — View Citation

Sisko AM, Truffer CJ, Keehan SP, Poisal JA, Clemens MK, Madison AJ. National health spending projections: the estimated impact of reform through 2019. Health Aff (Millwood). 2010 Oct;29(10):1933-41. doi: 10.1377/hlthaff.2010.0788. Epub 2010 Sep 9. Erratum In: Health Aff (Millwood). 2010 Nov;29(11):2128. — View Citation

Slymen DJ, Hovell MF. Cluster versus individual randomization in adolescent tobacco and alcohol studies: illustrations for design decisions. Int J Epidemiol. 1997 Aug;26(4):765-71. doi: 10.1093/ije/26.4.765. — View Citation

Spandorfer JM, Israel Y, Turner BJ. Primary care physicians' views on screening and management of alcohol abuse: inconsistencies with national guidelines. J Fam Pract. 1999 Nov;48(11):899-902. — View Citation

Spirito A, Monti PM, Barnett NP, Colby SM, Sindelar H, Rohsenow DJ, Lewander W, Myers M. A randomized clinical trial of a brief motivational intervention for alcohol-positive adolescents treated in an emergency department. J Pediatr. 2004 Sep;145(3):396-402. doi: 10.1016/j.jpeds.2004.04.057. — View Citation

Srisurapanont M, Sombatmai S, Boripuntakul T. Brief intervention for students with methamphetamine use disorders: a randomized controlled trial. Am J Addict. 2007 Mar-Apr;16(2):111-6. doi: 10.1080/10550490601184431. — View Citation

Sterling S, Chi F, Campbell C, Weisner C. Three-year chemical dependency and mental health treatment outcomes among adolescents: the role of continuing care. Alcohol Clin Exp Res. 2009 Aug;33(8):1417-29. doi: 10.1111/j.1530-0277.2009.00972.x. Epub 2009 Apr 30. — View Citation

Sterling S, Kohn C, Lu Y, Weisner C. Pathways to chemical dependency treatment for adolescents in an HMO. J Psychoactive Drugs. 2004 Dec;36(4):439-53. doi: 10.1080/02791072.2004.10524427. — View Citation

Sterling S, Weisner C, Hinman A, Parthasarathy S. Access to treatment for adolescents with substance use and co-occurring disorders: challenges and opportunities. J Am Acad Child Adolesc Psychiatry. 2010 Jul;49(7):637-46; quiz 725-6. doi: 10.1016/j.jaac.2010.03.019. Epub 2010 May 8. — View Citation

Sterling S, Weisner C. Chemical dependency and psychiatric services for adolescents in private managed care: implications for outcomes. Alcohol Clin Exp Res. 2005 May;29(5):801-9. doi: 10.1097/01.alc.0000164373.89061.2c. Erratum In: Alcohol Clin Exp Res. 2005 Oct;29(10):1914. — View Citation

Sterling S, Weisner C. Improving retention among women in substance abuse treatment: Is childcare enough? 129th meeting of the American Public Health Association, Atlanta, GA, 2001

Sterling S, Weisner C. The role of primary care in addressing adolescent substance use: Screening, treatment, and coordination. Paper presented at the

Sterling S, Weisner C. Translating research findings into practice: example of treatment services for adolescents in managed care. Alcohol Res Health. 2006;29(1):11-8. — View Citation

Substance Abuse and Mental Health Services Administration. SAMHSA Report to Congress - Nov 2002. The prevention and treatment of co-occurring substance abuse disorders and mental disorders. Rockville, MD, 2002. http://www.samhsa.gov/reports/congress2002/CoOccurringRpt.pdf. Accessed Oct 25, 2010

Suzuki K, Takeda A, Murakami S, Yuzuriha T, Hiezima M, Yoshimori C, Fuzibayashi T. [Brief intervention for smoking, problem drinking and drug abuse by high school students]. Nihon Arukoru Yakubutsu Igakkai Zasshi. 2003 Dec;38(6):475-82. Japanese. — View Citation

Tait RJ, Hulse GK, Robertson SI, Sprivulis PC. Emergency department-based intervention with adolescent substance users: 12-month outcomes. Drug Alcohol Depend. 2005 Sep 1;79(3):359-63. doi: 10.1016/j.drugalcdep.2005.03.015. Epub 2005 Apr 26. — View Citation

Thatcher DL, Clark DB. Adolescents at risk for substance use disorders: role of psychological dysregulation, endophenotypes, and environmental influences. Alcohol Res Health. 2008;31(2):168-76. — View Citation

Underage Drinking Enforcement Training Center. Welcome to the Underage Drinking Enforcement Training Center. http://www.udetc.org/index.asp. Updated Oct 2010. Accessed Oct 27, 2010

Van Den Eeden SK, Tanner CM, Bernstein AL, Fross RD, Leimpeter A, Bloch DA, Nelson LM. Incidence of Parkinson's disease: variation by age, gender, and race/ethnicity. Am J Epidemiol. 2003 Jun 1;157(11):1015-22. doi: 10.1093/aje/kwg068. — View Citation

Volk RJ, Steinbauer JR, Cantor SB. Patient factors influencing variation in the use of preventive interventions for alcohol abuse by primary care physicians. J Stud Alcohol. 1996 Mar;57(2):203-9. doi: 10.15288/jsa.1996.57.203. — View Citation

Weisner C, Delucchi K, Matzger H, Schmidt L. The role of community services and informal support on five-year drinking trajectories of alcohol dependent and problem drinkers. J Stud Alcohol. 2003 Nov;64(6):862-73. doi: 10.15288/jsa.2003.64.862. — View Citation

Weisner C, Matzger H. Missed opportunities in addressing drinking behavior in medical and mental health services. Alcohol Clin Exp Res. 2003 Jul;27(7):1132-41. doi: 10.1097/01.ALC.0000075546.38349.69. — View Citation

Weisner C, Mertens J, Parthasarathy S, Moore C, Hunkeler EM, Hu T, Selby JV. The outcome and cost of alcohol and drug treatment in an HMO: day hospital versus traditional outpatient regimens. Health Serv Res. 2000 Oct;35(4):791-812. — View Citation

Weisner C, Mertens J, Parthasarathy S, Moore C, Lu Y. Integrating primary medical care with addiction treatment: a randomized controlled trial. JAMA. 2001 Oct 10;286(14):1715-23. doi: 10.1001/jama.286.14.1715. — View Citation

Weisner C, Schmidt LA. Rethinking access to alcohol treatment. Recent Dev Alcohol. 2001;15:107-36. doi: 10.1007/978-0-306-47193-3_7. No abstract available. — View Citation

Westermeyer J, Doheny S, Stone B. An assessment of hospital care for the alcoholic patient. Alcohol Clin Exp Res. 1978 Jan;2(1):53-7. doi: 10.1111/j.1530-0277.1978.tb04694.x. — View Citation

Whitmore EA, Mikulich SK, Thompson LL, Riggs PD, Aarons GA, Crowley TJ. Influences on adolescent substance dependence: conduct disorder, depression, attention deficit hyperactivity disorder, and gender. Drug Alcohol Depend. 1997 Aug 25;47(2):87-97. doi: 10.1016/s0376-8716(97)00074-4. — View Citation

Wibbelsman CJ. Confidentiality in an Age of Managed Care: Can It Exist? Adolesc Med. 1997 Oct;8(3):427-432. — View Citation

Wilson CR, Sherritt L, Gates E, Knight JR. Are clinical impressions of adolescent substance use accurate? Pediatrics. 2004 Nov;114(5):e536-40. doi: 10.1542/peds.2004-0098. — View Citation

Windle M, Spear LP, Fuligni AJ, Angold A, Brown JD, Pine D, Smith GT, Giedd J, Dahl RE. Transitions into underage and problem drinking: developmental processes and mechanisms between 10 and 15 years of age. Pediatrics. 2008 Apr;121 Suppl 4(Suppl 4):S273-89. doi: 10.1542/peds.2007-2243C. — View Citation

Winters KC, Leitten W, Wagner E, O'Leary Tevyaw T. Use of brief interventions for drug abusing teenagers within a middle and high school setting. J Sch Health. 2007 Apr;77(4):196-206. doi: 10.1111/j.1746-1561.2007.00191.x. — View Citation

Wu NS, Lu Y, Sterling S, Weisner C. Family environment factors and substance abuse severity in an HMO adolescent treatment population. Clin Pediatr (Phila). 2004 May;43(4):323-33. doi: 10.1177/000992280404300403. — View Citation

Yoast RA, Fleming M, Balch GI. Reactions to a concept for physician intervention in adolescent alcohol use. J Adolesc Health. 2007 Jul;41(1):35-41. doi: 10.1016/j.jadohealth.2007.02.008. Epub 2007 May 3. — View Citation

* Note: There are 160 references in allClick here to view all references

Outcome

Type Measure Description Time frame Safety issue
Primary Screening rate The proportion of patients who are screened with the Teen Well Check Questionnaire AOD use or Mood symptom questions, among all patients with Teen well-child visits. Initial screening rate - at index well-visit
Primary Problem Identification rate The proportion of patients screened who answer "yes" to AOD use or Mood symptoms in past 12 months and "yes" to at least one non-car CRAFFT question. (Being in a car with someone using AOD may not be related to child's problem, but to having a parent/other adult who has driven while drinking/using). Initital problem identification rate - at index well-visit, following screening
Primary Assessment rate Proportion of patients screening positive for alcohol or other drug, or mental health risk, who are assessed further using the CRAFFT tool. Within 2 weeks following index well-visit date
Primary Brief Intervention rate The proportion of patients who receive an intervention within 14 days, among those who are identified with AOD risk (based on CRAFFT score). Documented in EHR by clinicians, using an ICD-9 Administrative V-code for substance use counseling or behavioral counseling. Within 14 days of assessment at index well visit
Primary Referral to specialty treatment rate The proportion of patients who receive referrals to specialty behavioral health treatment, among those identified through the CRAFFT as needing such treatment. Documented in the EHR. Within 6 months of index well-visit
Secondary Specialty Behavioral Health Treatment Initiation Defined as the percent referred, who have at least one specialty behavioral health visit among those identified with a behavioral health problem. Documented in the EHR. Within 2 years post-intervention
Secondary Alcohol and other drug use Alcohol and drug use: The items in the EHR measure past 30-day and 6-month use of alcohol, marijuana and other drugs and tobacco, including days of use, quantity consumed (any, 3+ and 5+ drinks), and days of binge drinking (3+ and 5+). Use in past 6 months, at 1 and 2 years post-intervention
Secondary Substance Use-related outcomes AOD-related legal, school, and family problems: The EHR questions also include measures from the Comprehensive Adolescent Severity Inventory (CASI),148 a semi-structured questionnaire which measures adolescent health and functioning across education, legal, and family relations domains. in past 6 months, at 1 and 2 years post-intervention
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