Substance-related Disorder Clinical Trial
Official title:
French Study on COgnitive Enhancement and Consumption of Psychoactive Substances Among Youth Students (Enquête Nationale Sur le Dopage Intellectuel et Les Consommations de Substances Psychoactives Chez Les Jeunes étudiants)
This descriptive and declarative study will help to find out consumption rates, all psychoactive substances taken together, among 18-25 year olds. More specifically, it will allow assessment of the extent of the cognitive enhancement phenomenon among students in France (including study of misuse of methylphenidate (MPH) and modafinil in improvement of cognitive performance).
This descriptive and declarative study will help to find out consumption rates, among 18-25
year olds, all psychoactive substances (PAS) taken together. More specifically, it will allow
assessment of the extent of the cognitive enhancement phenomenon among students in France
(including study of misuse of methylphenidate (MPH) and modafinil, two drugs diverted from
their indications for improvement of cognitive performance).
Since Faculties of Sciences and Technics of Physical and Sports Activities (UFR STAPS) are
involved in the study, the issue of doping in Sports will also be addressed.
The main aim of this national study will be to assess for two successive academic years the
proportion and motives of consumption of PAS as part of cognitive enhancement among students
in real life.
Secondary aims will be: assessing consumption of PAS and desired effects when such
consumption beyond cognitive enhancement (experimental, recreational, abusive or therapeutic
use) but also comparing PAS uses in terms of a variety of characteristics (sex, age, field,
year of study) and finally to consider more broadly the health of students in a doping
behavior (impact of the use of products on health, whether cognitive enhancement is found to
be ethically acceptable or not).
The study will be conducted during a period of 3 years, between September 2016 and September
2019, according to a standardized methodology identical in every school involved and a
procedure based on an online self-administrated and anonymous survey questionnaire. The
questionnaire, elaborated on Limesurvey®, will be available for two successive academic years
for all students aged more than 18 years old. It is set up and hosted on a secured
high-capacity web server via the website of AP-HP.
The study will also search to assess the level of representation of the sample of respondents
regarding the general population of students. Various criteria: the proportion of subjects by
field, the proportion of respondents by study year and the sex ratio will be compared to data
of general statistics from the Ministry of Research and Higher Education. A representative
sample will allow us to assimilate our respondents to the general population of students and
estimate the prevalence of PAS consumption among students.
METHODS
For each product, a descriptive analysis of frequency will be done (consumption pattern,
consumer's opinion, feeling of dependency, efficacy of the product). For those most
frequently used, complementary analysis will be done in order to identify particular
profiles.
On the statistical level, univariate analysis will be performed using the Chi-square test and
analysis of variance. Then, multivariate analysis will allow us to study independent factors
such as age and study year for instance.
The number of respondents expected is approximately 30 000. The sample will also allow us to
identify factors associated with PAS consumption (MPH or modafinil particularly) by
multivariate modeling using a "split" of the sample procedure with one half used for the
construction of the model and the other for its validation.
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