Effects of Recursive Self-feedback on Speech Production in Aphasia

Stroke Clinical Trial

Official title:

Recursive Self-feedback Procedures for Improving Spontaneous Speech Production in Patients With Chronic Aphasia

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT06323629
• Other study ID #: STUDY006201
• Status: Not yet recruiting
• Phase: N/A
• Start date: April 2024
• Est. completion date: March 2025

Study information

• Verified date: March 2024
• Source: University of South Florida
• Contact: Gerald C. Imaezue, PhD
• Phone: (813)974-2464
• Email: gimaezue[@]usf.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The goal of this clinical trial is to test the effects of recursive self-feedback procedures on spontaneous speech production in stroke survivors with impaired speech production (aphasia). The main question it aims to answer is:

• To what extent can stroke survivors with aphasia use their self-feedback alone to improve their spontaneous speech production?

Participants will be engaged in the following activities:

• They will perform language and cognitive tasks.

• Afterwards, they will receive treatments using tablets and headphones at no cost to them.

• The experimental treatments (recursive self-feedback procedures) entails responding to prompts, listening to playbacks of their speech response and attempt to minimize/correct the errors in the next attempt. This process will be repeated multiple times per prompt.

• The experimental treatments are two: an adaptive version that adapts the complexity of the treatment prompt and a non-adaptive version that does not adapt task complexity.

• Researchers will compare the experimental treatments to see if both have similar effects on improving spontaneous speech production.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 45
• Est. completion date: March 2025
• Est. primary completion date: March 2025
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 80 Years

Eligibility

Inclusion Criteria:

• 6 months post left hemisphere stroke

• Aphasia due to left hemisphere stroke

• Dominant English speaker

Exclusion Criteria:

• Speech-language deficits due to neurological insults such as Parkinson's disease, neurodegenerative conditions etc.

• Uncorrected sensory impairments.

• Language comprehension impairment.

• Severe cognitive impairment.

Related Conditions & MeSH terms

• Aphasia
• Stroke

Intervention

Behavioral:
• Adaptive recursive self-feedback procedure
The intervention uses self-feedback alone to improve speech production. It adapts the complexity of the treatment tasks.
• Non-adaptive recursive self-feedback procedure
The intervention uses self-feedback alone to improve speech production. However, it does not adapt the complexity of the treatment tasks.

Locations

Country	Name	City	State
n/a

Sponsors (2)

Lead Sponsor	Collaborator
University of South Florida	Center for Smart Use of Technologies to Assess Real-world Outcomes

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Speaking rate	Correct words produced per minute	Within 1 week before treatment and within 1 week after treatment.
Primary	Speech initiation latency in milliseconds	Latency before retrieving the first correct word in an utterance.	Within 1 week before treatment and within 1 week after treatment.