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Personalized Transcranial Direct Current Stimulation in Stroke Recovery

Stroke Clinical Trial

Official title:
Personalized Transcranial Direct Current Stimulation in Stroke Recovery

Clinical Trial Summary

The central objective of this application is to explore the neural substrate of personalized tDCS (ptDCS) and to determine whether the paradigm for each stroke patient can predict the amount of sustained clinical improvement through increased connectivity as measured by a biomarker of plasticity.

Clinical Trial Description

This is a randomized, sham controlled double masked parallel group study with optional crossover of chronic (>3mo from stroke onset) ischemic or hemorrhagic stroke patients to test the effect of ptDCS on a cerebral connectivity biomarker of plasticity during stimulation and after 10 treatment of up to 2 mA ptDCS. PtDCS will be performed during the first 20 minutes of occupational therapy targeting the weaker arm compared to sham. Patients will have the option to cross over after the completion of 1-month follow-up and will complete the same procedures with real tDCS if they were in the sham group. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06286800
Study type Interventional
Source The Methodist Hospital Research Institute
Contact Meyyammai Narayanan, MPH
Phone 9082277275
Email mknarayanan@houstonmethodist.org
Status Not yet recruiting
Phase N/A
Start date March 14, 2024
Completion date September 14, 2026
View Details
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