The Effect of Covered Eye Walking on Electroencephalogram in Stroke Patients Compared With Open Eye Walking

Stroke Clinical Trial

Official title:

Study of Visual Deprivation on EEG Signal in Stroke Patients

Clinical Trial Details — Status: Suspended

Administrative data

• NCT number: NCT06234618
• Other study ID #: ZD2022065
• Status: Suspended
• Start date: February 28, 2024
• Est. completion date: June 30, 2024

Study information

• Verified date: April 2024
• Source: Nanjing Medical University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Post-stroke walking abnormalities present significant rehabilitation challenges. Visual deprivation training has been shown to be more effective than open-eye training. The investigators intend to examine the changes in electroencephalography patterns in stroke patients during visually deprived walking tasks.

The stroke participants will be fitted with a brain cap. The participants will walk with their eyes open for 60 seconds, and then their eyes will be blindfolded as they continue walking for another 60 seconds. Electroencephalography will monitor the signals in real-time during both walks.

Description:

The electroencephalography data collection will be conducted in the Rehabilitation Department of Geriatric Hospital Affiliated with Nanjing Medical University. Upon commencing the experiment, participants will walk at a comfortable pace with their eyes open for a duration of 60 seconds. Following this initial test, a rest period of five minutes will be provided. For the visual deprivation walking trial, participants will be instructed to keep their eyes open throughout the trial. Investigators will apply an adequately sized blindfold to ensure complete visual deprivation, and the participants will proceed to walk for 60 seconds. During both trials, one investigator will remain one step behind the participant at all times to ensure safety.

Recruitment information / eligibility

• Status: Suspended
• Enrollment: 5
• Est. completion date: June 30, 2024
• Est. primary completion date: June 30, 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 70 Years

Eligibility

Inclusion Criteria:

• Clinical diagnosis of stroke

• Disease duration of more than 14 days

• Ability to walk at least 10 m without assistance,

Exclusion Criteria:

• Visual impairment

• Severe cognitive impairment

Related Conditions & MeSH terms

• Stroke

Intervention

Other:
• visual deprivation
A group of patients walking with eyes open and walking with visual deprivation.

Locations

Country	Name	City	State
China	Geriatric Hospital of Nanjing Medical University	Nanjing	Jiangsu

Sponsors (1)

Lead Sponsor	Collaborator
Nanjing Medical University

Country where clinical trial is conducted

China, 

References & Publications (1)

Oliveira AS, Schlink BR, Hairston WD, Konig P, Ferris DP. Restricted vision increases sensorimotor cortex involvement in human walking. J Neurophysiol. 2017 Oct 1;118(4):1943-1951. doi: 10.1152/jn.00926.2016. Epub 2017 Jul 5. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	phase locking value	used to evaluate the phase synchronization relationship between two signals.	Real-time monitoring of electroencephalography data will occur while participants are walking. The Time Frame for data collection will encompass the entire duration of each participant's walking session, which lasts for 60 seconds.
Primary	phase lag Index	evaluate the degree of phase synchronization and the symmetry of neural oscillatory	Real-time monitoring of electroencephalography data will occur while participants are walking. The Time Frame for data collection will encompass the entire duration of each participant's walking session, which lasts for 60 seconds.

External Links

•   In this paper, the electroencephalography changes of normal people during visual deprivation walking were studied