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Neurobiomarker for Prism Adaptation Treatment Response

Stroke Clinical Trial

Official title:
Development of a Neuroimaging Biomarker to Identify Optimal Candidates for Prism Adaptation Treatment

Clinical Trial Summary

Preliminary data will be collected about which individuals with spatial neglect from right hemisphere stroke (aiming vs perceptual neglect) improve with Prism Adaptation Training and if there is a particular pattern of damage in the brain that predicts both the type of neglect experienced and whether neglect is improved following Prism Adaptation Training

Clinical Trial Description

For preliminary data, twelve individuals with right hemisphere stroke and spatial neglect will participate. After pretesting for type of neglect and its severity, they will have an MRI with Diffusion Tensor Imaging (DTI). Then they will complete 10 sessions of Prism Adaptation Therapy and complete neglect post-testing. Response to Prism Adaptation Therapy will be assessed by comparing neglect scores pre- and post-training. Traditional lesion mapping, structural and functional lesion disconnectivity analyses, and tract-based spatial statistics of DTI measures will be used to examine whether any patterns of damage/dysfunction are related to a diagnosis of aiming neglect and response to Prism Adaptation Therapy. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04966000
Study type Interventional
Source University of Utah
Contact
Status Not yet recruiting
Phase N/A
Start date January 2024
Completion date March 30, 2027
View Details
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