Stroke Clinical Trial
— MIRAAOfficial title:
MIRAA - A National Study on Intensive Rehabilitation of Aphasia and Apraxia of Speech Following Stroke
Verified date | March 2023 |
Source | Karolinska Institutet |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Positive outcomes have been shown following intensive treatment of speech and/or language impairment post stroke, but how to design intensive treatment programs to achieve optimal recovery and neuroplasticity changes needs to be further researched. The purpose of the MIRAA (Multimodal Intensive Rehabilitation of Aphasia and Apraxia of Speech) project is to study feasibility of intensive intervention for acquired aphasia and apraxia of speech (AOS) after stroke in the regular Swedish health-care according to the updated national guidelines from the Swedish National Board of Health and Welfare.
Status | Completed |
Enrollment | 25 |
Est. completion date | December 31, 2022 |
Est. primary completion date | December 31, 2022 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - Aphasia minimum 3 months post stroke - Apraxia of Speech minimum 3 months post stroke - Being able to participate in rehabilitation in Swedish (not in need of translator to partake). Exclusion Criteria: - Severe loss of sight - Severe loss of hearing - Severe cognitive decline |
Country | Name | City | State |
---|---|---|---|
Sweden | Karolinska Institutet, CLINTEC, Division of Speech and Language Pathology, F67, Karolinska University Hospital, Huddinge | Stockholm |
Lead Sponsor | Collaborator |
---|---|
Karolinska Institutet |
Sweden,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Evaluation of training, questionnaire to participating Speech and Language Pathologists | Minimum score 0, maximum score 12. Higher scores mean better outcome on satisfaction with intensive training and effects on speech, language and functional communication. | Directly after intensive treatment | |
Primary | Evaluation of training, questionnaire to participants | Minimum score 3, maximum score 12. Higher scores mean better outcome on satisfaction with intensive training and effects on speech, language and functional communication. | Directly after intensive treatment | |
Secondary | Comprehensive Aphasia Test (CAT) | Comprehensive Aphasia Test (CAT) language battery. Comprehension of spoken language: minimum score 0, maximum score 66; Comprehension of written language: minimum score 0, maximum score 62; Repetition: minimum score 0, maximum score 74; Naming: minimum score 0, maximum score no limit; Reading: minimum score 0, maximum score 70; Writing: minimum score 0, maximum score 76. Higher scores mean better outcome in language functions. | Changes from baseline in language battery scores at 6 and 16 (+-2) weeks. | |
Secondary | Boston Naming Test (BNT) | Minimum score 0, maximum score 60. Higher scores mean better outcome in naming ability. | Changes from baseline scores at 6 and 16 (+-2) weeks. | |
Secondary | Rating scale for apraxia of speech (SkaFTA, Swedish version of ASRS) | Minimum score 0, maximum score 52. Lower scores mean better outcome in speech functions. | Time Frame: Changes from baseline scores at 6 and 16 (+-2) weeks. | |
Secondary | Protocol for Apraxia of Speech (TAX) | Minimum score 0, maximum score 30. Lower scores mean mean better outcome in speech functions and non verbal oral apraxia. | Changes from baseline scores at 6 and 16 (+-2) weeks. | |
Secondary | Comprehensive Aphasia Test (CAT), subtest cognitive screening | Minimum score 0, maximum score 38. Higher scores mean better outcome in cognitive functions. | Changes from baseline scores at 6 and 16 (+-2) weeks. | |
Secondary | Communicative Effectiveness Index (CETI) | Minimum score 0, maximum score 100. Higher scores mean better outcome in communicative effectiveness. | Changes from baseline scores at 6 and 16 (+-2) weeks. | |
Secondary | General Health Questionnaire 12 questions (GHQ-12) | Minimum score 0, maximum score 36. Lower scores mean mean better outcome in general health. | Changes from baseline scores at 6 and 16 (+-2) weeks. |
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