Effects of High-intensity Aerobic Training on Balance, Walking Capacity, and Quality of Life in Patients With Sub-acute Stroke.

Stroke Clinical Trial

Official title:

Effect of High Intensity Speed Based Treadmill Training on Balance, Walking Capacity, and Quality in People With Sub-acute Stroke.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04752124
• Other study ID #: 555
• Status: Completed
• Phase: N/A
• Start date: November 7, 2020
• Est. completion date: March 15, 2021

Study information

• Verified date: March 2021
• Source: Government College University Faisalabad
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Stroke is one of the major cause of morbidity and mortality and the leading cause of disability in adults all around the world. Stroke survivors can suffer several neurological impairments and deficits which have an important impact on patient's quality of life and which increase the costs for health and social services. After stroke, impairments in ADLs and functional status, deterioration in health related quality of life can be seen.

The purpose of this study is to Determine the effect of high intensity speed based treadmill training on Balance, Walking capacity and quality of life in sub-acute stroke.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 50
• Est. completion date: March 15, 2021
• Est. primary completion date: February 27, 2021
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 90 Years

Eligibility

Inclusion Criteria:

• age 40-80 years; first episode of stroke; >4 weeks of stroke onset; hemiparesis resulting from unilateral ischaemic stroke; Ashworth score of 0 or 1, indicating no spasticity or slight spasticity over the affected lower limb, respectively; mini-mental state examination score =23; ability to perform independent walking for at least five minutes with or without an assistive device (FAC=3). All patients will be determined to be in stable cardiovascular condition with a low although slightly greater risk for vigorous exercise than for apparently healthy persons (class B according to the American College of Sports Medicine [ACSM]).13

Exclusion Criteria:

• Participants will be excluded from the study if they had any of the following: (1) chronic cardiorespiratory or metabolic diseases; (2) severe osteoporosis; and (3) lesions pertaining to the brainstem or cerebellum; (4) having resting blood pressure above 160/100 mmHg even after taking medications; (5) cardiovascular comorbidity (aortic stenosis, depression of ST-segment, heart failure, arrhythmias, unstable angina, hypertrophic cardio-myopathy); (6) transient ischemic attack; (7) by-pass surgery in the recent three months; and (8) other musculoskeletal problems that prevented the participants from doing aerobic activity.

Related Conditions & MeSH terms

• Stroke

Intervention

Other:
• Exercise Therapy
High intensity speed based interval treadmill training
• conventional therapy
conventional physical therapy

Locations

Country	Name	City	State
Pakistan	Bin Inam Rehabilitation Center.	Faisalabad	Punjab

Sponsors (1)

Lead Sponsor	Collaborator
Government College University Faisalabad

Country where clinical trial is conducted

Pakistan, 

References & Publications (1)

Lau KW, Mak MK. Speed-dependent treadmill training is effective to improve gait and balance performance in patients with sub-acute stroke. J Rehabil Med. 2011 Jul;43(8):709-13. doi: 10.2340/16501977-0838. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	6 minute walk test	To determine the endurance after stroke	6 weeks of training
Secondary	Berg Balance scale	It is used to measure the Balance and stability of patient. Total score of the scale is 56. A score of < 45 indicates individuals may be at greater risk of falling.	5 weeks
Secondary	Stroke Impact scale	To measure the impairment and quality of life after stroke. The maximum score is 140.	5 weeks