Stroke Clinical Trial
Official title:
Study of Spastic Cocontractions and Limitation of Active Movements of the Upper Limb Before and After Treatment During Injection of Botulinum Toxin in Patients After Stroke
Following a stroke , 55% of the patients do not recover any traction of the upper limb and
30% a residual motricity not allowing a functional grip. For this last group of patients,
there are major therapeutic issues to restore a functional grip.
The aim of the study is to relieved the spastic cocontractions before and after usual
injection of botulinum toxin A at stroke patient.
Descriptive study of spastic cocontraction index before and after botulinum toxin A
injections during active elbow extension in chronic vascular hemiplegic patients.
The spastic cocontraction score will be compared between T1 (before the Botulinum toxin A
injection) and T2 (4 weeks after the botulinum toxin A injection in the elbow flexors).
There is no control group. The patient is his own witness: the non-paretic side is considered
as the physiological reference in terms of the level of spastic cocontractions.
Botulinum toxin A injections are performed in routine clinical practice in the Physical
Medicine and Rehabilitation Department, following the recommendations in force. This
treatment has been shown to be effective on spasticity in several high-level studies. The
reduction of spasticity, evaluated clinically (Tardieu and Ashworth scale), is a criterion of
efficacy of botulinum toxin A injections.
The evaluation of the effectiveness of botulinum toxin A injections on the other components
of muscular hyperactivity, such as the reduction of spastic cocontraction during active
movements, is poorly performed in clinical and clinical research. This protocol includes
specific assessments to evaluate the evolution of spastic cocontraction.
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