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Clinical Trial Study About Human Adipose-Derived Stem Cells in the Stroke

Stroke Clinical Trial

Official title:
Adipose-Derived Stem Cells (ADSCs) Injections for Stroke

Clinical Trial Summary

The objective of the study is to confirm the safety and possible efficacy of Adipose-Tissue Derived Stem Cells treatment of chronic stroke. Specifically, the study will transplant autologous ADSCs into brain surrounding ischemic infarct in adult (65-80 years old) subjects who have chronic non-hemorrhagic stroke (>6 months).

Clinical Trial Description

This open-label clinical trial will compare outcomes of subjects with chronic stroke. Six subjects will be to treatment (n=3) groups. The treatment group will receive brain transplants of autologous ADSCs. Treatment group will receive rehabilitation after the transplantation. Subjects will be assessed by magnetic resonance imaging (MRI) and eight standardized stroke indices: National Institutes of Health Stroke Scale (NIHSS), ( Barthel Index )、 ( Berg balance scale )、 (Fugl - Meyer test )、(Action research arm test )、 (Purdue pegboard )、 ( grip strength measurement ) 、(somatosensory evoked potential, SSEP) at 1 month, 3 months, and 6 months after treatment. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02813512
Study type Interventional
Source Gwo Xi Stem Cell Applied Technology Co., Ltd.
Contact
Status Completed
Phase Phase 1
Start date October 19, 2017
Completion date November 27, 2018
View Details
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