A Longitudinal Study of Multimodal Resonance Imaging in Stroke Patients

Stroke Clinical Trial

Official title:

A Longitudinal Study of Multimodal Resonance Imaging in Stroke Patients

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT02024503
• Other study ID #: 2013CB733803
• Status: Recruiting
• Phase: N/A
• First received: December 25, 2013
• Last updated: December 30, 2013
• Start date: September 2013
• Est. completion date: December 2015

Study information

• Verified date: December 2013
• Source: Zhongda Hospital
• Contact: Cheng-yu Peng
• Email: 514974848[@]qq.com
• Is FDA regulated: No
• Health authority: China: Ministry of Health
• Study type: Observational

Clinical Trial Summary

Imaging of the ischaemic penumbra with a particular diffusion-weighted imaging (DWI)/ perfusion-weighted imaging (PWI) mismatch is a promising approach to the selection of patients with acute ischaemic stroke for trials of intervention. The investigators want to apply multimodal resonance imaging methods such as functional magnetic resonance imaging ( fMRI), diffusion tensor imaging (DTI), arterial spin labeling (ASL) to guide treatment and predict the prognosis of stroke.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 800
• Est. completion date: December 2015
• Est. primary completion date: May 2015
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 40 Years to 85 Years

Eligibility

Inclusion Criteria:

Time from the onset of stroke till hospital within 24 hours. With clinical characteristics such as hemiplegia, headache. Willing and able to comply with the study procedures and provide written informed consent to participate in the study.

Patients must understand the nature of the study and give informed consent.

Exclusion Criteria:

The onset of stroke out of 24 hours. Pregnant women. Patients with intracranial metallic bodies from prior neurosurgical procedure, implanted pacemaker, medication pump, vagal stimulator, deep brain stimulator, TENS unit or ventriculoperitoneal shunt.

Past history of seizures within one year or unexplained loss of consciousness. Family history of epilepsy.

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

• Stroke

Locations

Country	Name	City	State
China	Zhongda Hospital,Southeast University	Nanjing	Jiangsu

Sponsors (1)

Lead Sponsor	Collaborator
Zhongda Hospital

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Functional recovery		Participants will be followed till die or lost to follow-up,an expected average of three year.	No
Secondary	Over survival	Time from stenting to the day when the patients died or lost to the follow-up	Participants will be followed till die or lost to follow-up,an expected average of three year	No