Stroke Clinical Trial
The investigators aimed in this study to investigate the effects of 4 weeks robot-assisted
locomotor training on motor recovery of lower extremities and walking ability compared with
the conventional gait training in subacute post-stroke non-ambulatory hemiplegic patients.
72 first-ever stroke patients who could not walk independently (FAC < 2), and suffered
within 6 months were enrolled and randomly assigned into 2 groups. The subjects with
congestive heart failure, malignancies, cardiopulmonary dysfunctions, and who could not walk
independently before stroke attack were excluded.
Two groups received 30 minutes conventional gait training including Neurodevelopmental
Treatment (NDT) basically. The robotic assisted locomotor training group received additional
robotic-assisted gait therapy for 30minutes with Lokomat® (Hocoma, Zurich, Switzerland)
daily for 4 weeks, and the conventional gait training group received additional daily
conventional gait training with NDT for the same periods. The independent walking
ability(FAC ≥ 3), Functional Ambulation Category (FAC), Motricity index (MI), Fugl-Meyer
assessment (FMA), Modified Barthel Index (MBI), Medical Research Council (MRC) for each
lower extremity muscles were assessed before, during (2weeks) and after training. And the
independent walking ability were followed until 3 months.
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
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