Strength Training for Chronic Stroke Patients

Stroke Clinical Trial

Official title:

Maximal Strength Training for Chronic Phase Stroke Patients

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01003353
• Other study ID #: 2009/1241
• Status: Completed
• Phase: N/A
• First received: October 27, 2009
• Last updated: June 22, 2012
• Start date: November 2009
• Est. completion date: March 2010

Study information

• Verified date: June 2012
• Source: Norwegian University of Science and Technology
• Contact: n/a
• Is FDA regulated: No
• Health authority: Norway: Norwegian Social Science Data Services
• Study type: Interventional

Clinical Trial Summary

The study aims to investigate the effects of strength training on maximal strength, walking ability and neural function in chronic stroke patients. The strength training intervention in this study is different to all previous interventions for stroke patients.

Maximal Strength Training (MST) involves weights of up to 90% of the participants 1 repetition maximum and has a focus on the explosive development of force. This study will use these principles for unilateral leg press and plantarflexion exercises. Only 2 previous studies have investigated high intensity strength training for stroke patients and they used intensities of 80% 1RM. Previous MST interventions have shown large increases in strength, rate of force development and this has transferred to improved walking economy.

The investigators predict that MST will give large increases in strength, improved rate of force development (RFD) and walking economy. The investigators expect that better neural function will account for the improvements. This study could provide evidence for the adoption of a completely different method of strength rehabilitation for stroke survivors.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 10
• Est. completion date: March 2010
• Est. primary completion date: March 2010
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years to 67 Years

Eligibility

Inclusion Criteria:

• Under 67 years old

• Suffered from a stroke at least 6 months previously

• Living in the Trondheim area such that travel costs can be covered by 1500 NOK

• Must be able to walk, although use of aids is permitted

Exclusion Criteria:

• Participants must not have cognitive, visuospatial or comprehension deficits to magnitude such that it interferes with the ability to perform testing and training

• Participants must be medically unstable (e.g. uncontrollably high blood pressure (140/90), arrythmia, other heart instabilities or other known comorbid diseases)

• Participants must not be known to be pregnant

Study Design

Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

• Stroke

Intervention

Behavioral:
• Maximal strength training
Training will be carried out 3 times a week for 8 weeks. Each session will include a warm up, strength training and warm down. The total time will be approximately 1 hour. The training will consist 2 exercises (leg press and plantarflexion). Participants will train each leg individually with 4 sets of 4 repetitions at 90% of the 1 repetition maximum.

Locations

Country	Name	City	State
Norway	Avdeling for ervervede hjerneskader, Klinikk for fysikalsk medisin og rehabilitering, St Olavs Hospital	Trondheim

Sponsors (1)

Lead Sponsor	Collaborator
Norwegian University of Science and Technology

Country where clinical trial is conducted

Norway, 

References & Publications (1)

Hill TR, Gjellesvik TI, Moen PM, Tørhaug T, Fimland MS, Helgerud J, Hoff J. Maximal strength training enhances strength and functional performance in chronic stroke survivors. Am J Phys Med Rehabil. 2012 May;91(5):393-400. doi: 10.1097/PHM.0b013e31824ad5b — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Unilateral 1 repetition maximum for leg press and plantarflexion		November 2009-March 2010	No
Secondary	Rate of force development in unilateral leg press and plantarflexion		November 2009 - March 2010	No
Secondary	Maximal oxygen uptake and walking economy		November 2009 - March 2010	No
Secondary	Timed Up and Go Test		November 2009 - March 2010	No
Secondary	4 Step Balance Test		November 2009 - March 2010	No
Secondary	V-Wave (using sEMG equipment) of soleus during static plantarflexion		November 2009 - March 2010	No
Secondary	Blood lipid profile		November 2009 - March 2010	No
Secondary	6 Minute Walk Test		November 2009 - March 2010	No
Secondary	Jump Height of a countermovement jump		November 2009 - March 2010	No
Secondary	SF-36 Quality of life questionnaire, Norwegian version		November 2009 - March 2010	No