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Neuroregeneration Enhanced by Transcranial Direct Current Stimulation (TDCS) in Stroke — NETS  

Stroke Clinical Trial

Official title:
Neuroregeneration Enhanced by TDCS in Stroke

Clinical Trial Summary

Testing the hypothesis that non-invasive brain stimulation by transcranial direct current stimulation (tDCS) combined with functional training in the subacute phase of first-ever stroke will enhance functional regeneration compared with a Placebo intervention.

Clinical Trial Description

Stroke is the leading cause of long-term disability, which significantly impairs the economic and social life of patients and society. Every year 200 000 to 250 000 patients suffer a stroke in Germany. Only a small number of the stroke survivors recover to a degree that allows them to return into their professional and private life. Despite significant efforts to develop novel and efficient treatment strategies the level of functional regeneration is still not satisfying. Thus, the development of innovative and effective treatment strategies will have a major impact for the patients' life, the society and the public health system. Within the proposed project an innovative, non-invasive and cost effective interventional strategy, based on the combination of a specific rehabilitative training and brain stimulation by transcranial direct current stimulation (tDCS), will be used to enhance functional regeneration in stroke patients. The intervention will be applied in an early stage in which plasticity, cortical reorganization and functional improvement is most pronounced. We hypothesize that the combination of anodal tDCS delivered to the motor cortex of the affected hemisphere combined with training over a period of two weeks in the subacute stage after stroke will significantly enhance cortical plasticity, functional regeneration and long-term outcome determined by clinical and functional outcome measures compared with Placebo stimulation. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00909714
Study type Interventional
Source Universitätsklinikum Hamburg-Eppendorf
Contact
Status Active, not recruiting
Phase N/A
Start date July 2009
Completion date September 30, 2021
View Details
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