Stroke Clinical Trial
— CADISSOfficial title:
Cervical Artery Dissection in Stroke Study
This is a feasibility study to determine if a sufficient number of patients can be recruited throughout the United Kingdom and whether sufficient endpoints can be generated for a full scale therapeutic trial of anticoagulants versus antiplatelets in acute cervical artery dissection treatment.
Status | Completed |
Enrollment | 250 |
Est. completion date | May 2014 |
Est. primary completion date | |
Accepts healthy volunteers | No |
Gender | Both |
Age group | N/A and older |
Eligibility |
Inclusion Criteria: 1. Extracranial carotid or vertebral artery dissection with symptom onset within the last 7 days. This includes: 1. Ipsilateral transient ischemic attack or stroke 2. Ipsilateral Horner's syndrome or neck pain with known date of onset. 2. Imaging evidence of definite or probable dissection on MRI/MRA, CTA or ultrasound. Exclusion Criteria: 1. Intracranial cerebral artery dissection 2. Symptom onset after 7 days 3. Contraindication to either antiplatelet agents or anticoagulation therapy 4. Patient's refusal to consent 5. Patients who are undergoing angiography and stenting or surgery for treatment of their dissection. |
Allocation: Randomized, Endpoint Classification: Bio-equivalence Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
United Kingdom | St. George's University of London, Clinical Neuroscience Department, Cranmer Terrace | London | England |
Lead Sponsor | Collaborator |
---|---|
St George's, University of London | The Stroke Association, United Kingdom |
United Kingdom,
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