Stroke Clinical Trial
Official title:
Balance Recovery and Training on Fall Prevention in Stroke
The specific aims of this research are delineated as the following:
Aim 1: To investigate the neuromuscular and biomechanical mechanisms of the emerging
processes of proactive and reactive balance control during sitting and standing in patients
with stroke at different stages of the recovery course.
Aim 2: To determine the relationships between brain lesion sites and the recovery patterns
of reactive and proactive balance control mechanisms in patients with stroke.
Aim 3: To determine the relationships between the impairments in reactive and proactive
balance control mechanisms and functional outcome as well as fall incidence in patients
following stroke.
Aim 4: To investigate the efficacy of different training regimens in improving reactive and
proactive balance control strategies and in preventing falls in stroke patients with
different brain lesion sites.
Principally, three hypotheses are to be tested:
Hypothesis 1:The emerging processes and recovery patternes of proactive and reactive balance
control may be different among stroke patients with different brain lesion locations.
Hypothesis 2:There are positive correlations between the level of impairments in reactive
and proactive balance control mechanisms and functional outcome as well as fall incidence in
patients following stroke.
Hypothesis 3:Training regimens that could best facilitate the emergence or improvement in
reactive and proactive balance control strategies are different.
Stroke is one of the leading causes of chronic disability in the world. Falls are one of the primary complications after stroke. The incidence of falls ranges from 25% to 75% among stroke patients residing in different settings, with greater incidence of falls occurring after discharge home. Postural instability has been suggested as one of the main causes leading to falls in this population. The recovery of the ability to maintain balance during activities of daily living, therefore, is essential for functional independence and safety of these patients. In the following paragraphs, the knowledge gaps taht we are proposing to bridge in this study and the revelant literature that leads us to identify these gaps are discussed. ;
Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Educational/Counseling/Training
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