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Remote Ischemic Limb Preconditioning In Healthy Volunteers

Stroke Clinical Trial

Official title:
Does Remote Ischemic Limb Preconditioning Improve Cerebral Vasomotor Reactivity in Healthy Volunteers?

Clinical Trial Summary

The investigators would like to determine if remote ischemic leg preconditioning in healthy volunteers improves cerebral vasomotor reactivity as measured by breath holding and transcranial doppler vasomotor reactivity.

Clinical Trial Description

This study is to determine if remote ischemic leg preconditioning improves short and long term cerebral vasomotor reactivity in healthy volunteers as measured by breath holding and transcranial doppler vasomotor reactivity. Previous studies on brachial vasomotor reactivity have shown a beneficial effect of remote ischemic preconditioning. It remains uncertain if a similar beneficial effect can be reproduced with cerebral vasomotor testing. Many biological mechanisms and effector pathways triggered by preconditioning have demonstrated endothelial protection and beneficial vascular effects. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02553655
Study type Interventional
Source University of Miami
Contact
Status Completed
Phase N/A
Start date October 2015
Completion date June 3, 2021
View Details
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