Clinical Trials Logo
  1. Home
  2. Stroke Rehabilitation
  3. NCT04459091

Effects of Supplementation With Amino Essential Acids on Circulating Albumin Levels in Stroke in Rehabilitation Phase

Stroke Rehabilitation Clinical Trial

Official title:
Effects of Supplementation With Amino Essential Acids on Circulating Albumin Levels in Patients With Cerebral Ictus in Rehabilitation Phase

Clinical Trial Summary

In addition to its physiological functions, serum albumin plays a role of neuroprotection in cerebrovascular stroke. The circulating levels of albumin may be reduced in patients with stroke due to the presence of a systemic inflammatory state and to the inadequacy of protein-energy intake. The circulating levels of albumin have proven to be predictors of functional recovery in ischemic stroke and cerebral hemorrhage. In the present survey it is hypothesized that it is possible to significantly improve the values of hypoalbuminemia by supplementation with essential amino acids and that, in the second place, any increase in albumin may result in a strengthening of functional recovery in patients with a stroke.

Clinical Trial Description

In addition to its physiological functions, serum albumin plays a role of neuroprotection in cerebrovascular stroke. The circulating levels of albumin may be reduced in patients with stroke due to the presence of a systemic inflammatory state and to the inadequacy of protein-energy intake. In the patients admitted to the Montescano Neuromotor Rehabilitation Division, the prevalence of hypoalbuminemia is high at the time of admission and remains high, even if decreased, at discharge. The circulating levels of albumin have proven to be predictors of functional recovery in ischemic stroke and cerebral hemorrhage. In the present survey it is hypothesized that it is possible to significantly improve the values of hypoalbuminemia by supplementation with essential amino acids and that, in the second place, any increase in albumin may result in a strengthening of functional recovery in patients with a stroke. Several factors induce the use of free essential amino acids: they are the most efficient inducers of protein synthesis and albumin is a protein; free essential amino acids and not those contained in proteins allow a more reliable use of the isoleucine and tryptophan, true nutrients limiting the hepatic synthesis of albumin; the free essential amino acids have a faster and complete intestinal absorption of the essential amino acids derived from protein digestion. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04459091
Study type Interventional
Source Istituti Clinici Scientifici Maugeri SpA
Contact
Status Completed
Phase N/A
Start date January 10, 2018
Completion date September 15, 2018
View Details
See also
  Status Clinical Trial Phase
Completed NCT03031977 - Visceral Mobilization and Functional Constipation in Stroke Survivors N/A
Not yet recruiting NCT04378946 - Error Augmentation Motor Learning Training Approach in Stroke Patients N/A
Recruiting NCT05690165 - Effects of Aerobic Exercise During the Early Rehabilitation After Ischemic Stroke N/A
Not yet recruiting NCT06053970 - Study Evaluating the Effect of Moving Virtual Scenes on Postural Balance in a Stroke Rehabilitation Setting N/A
Completed NCT03023150 - Ischemic Preconditioning as an Intervention to Improve Stroke Rehabilitation - Froedtert N/A
Terminated NCT04014270 - Self-modulated Functional Electrical Stimulation in Chronic Stroke Patients With Severe and Moderate Upper Limb Paresis N/A
Not yet recruiting NCT06128187 - The Effect of Dual Task Training on Upper Extremity Functions in Stroke Patients N/A
Completed NCT03773653 - Synergistic Bilateral Upper-Limb Stroke Rehabilitation Based on Robotic Priming Technique N/A
Recruiting NCT05505201 - Effectiveness of Transcranial Magnetic Stimulation in Subacute Stroke Patients With Severe Upper Limb Paresis N/A
Recruiting NCT04800601 - Walking Ankle isoKinetic Exercise N/A
Recruiting NCT05993091 - Mirror Therapy and Augmented Reality in Stroke Rehabilitation N/A
Recruiting NCT04682223 - Telerehabilitation for Aphasia (TERRA) N/A
Completed NCT03165630 - Stroke Patients' Outpatient Rehabilitation Therapy (SPORT) N/A
Recruiting NCT05944666 - Substantiation and Standardization of the Multimodal Cognitive-motor Rehabilitation System for Afterstroke Patients N/A
Enrolling by invitation NCT05447754 - Comparison of the Effects of Robotic Rehabilitation Versus Traditional Balance Training on Balance and Fear of Falling in Stroke Patients N/A
Completed NCT03798340 - Vibratory Perturbation-based Pinch Task Training for Stroke Patients N/A
Completed NCT02603718 - An Applicative On-line EEG Tool for Enhancing Treatment Efficacy N/A
Completed NCT05391919 - Multimodal Correction of Post-stroke Motor and Cognitive Impairments N/A
Recruiting NCT05945212 - Effects of Local Vibrations Program of Dorsiflexor Muscles on Neuromotor Recovery in Subacute Stroke Patients. N/A
Completed NCT04753931 - Effects of Sensory Training Application in Addition to Bobath Training N/A