Emotions Analysis in Patients With Chronic Phase of Stroke Basal Ganglia

Stroke Basal Ganglia Clinical Trial

— KALISS  

Official title:

Emotions Analysis in Patients With Chronic Phase of Stroke Basal Ganglia: Neuropsychological and Neurophysiological Study of Changes in Emotional Experiences

Clinical Trial Details — Status: Terminated

Administrative data

• NCT number: NCT02884882
• Other study ID #: KALISS RB10.077
• Status: Terminated
• Phase: N/A
• Start date: December 2011
• Est. completion date: April 2018

Study information

• Verified date: November 2018
• Source: University Hospital, Brest
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Compare the emotional experience of patients with focal lesions of the basal ganglia by ischemic or hemorrhagic damage and healthy participants. These anomalies will be highlighted by neuropsychological and electrophysiological assessments.

Recruitment information / eligibility

• Status: Terminated
• Enrollment: 149
• Est. completion date: April 2018
• Est. primary completion date: April 2018
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 70 Years

Eligibility

Inclusion Criteria:

• For cases :

• right-handed patient

• ischemic or hemorrhagic stroke older than 3 months with single lesion preferably less than 20 mm in diameter affecting the basal ganglia and sparing cortex

• Rankin score estimated prior stroke must be equal to 0 and after stroke <3 (at inclusion).

• For participants control : right-handed patient

Exclusion Criteria:

• For cases : severe aphasia - Prosopagnosia apperceptive - cerebral neurological pathology associated history, especially dementia - History of depression and psychiatric disorders treated - another stroke vascular territory than that for which the patient is included - diffuse lesions of the white matter Fazekas a score of> 2 (periventricular or subcortical) - Contraindications to MRI

• For participants control : No history neurosurgical - No history of head trauma with loss of consciousness - not known neurological disease - not known psychiatric illness
• No psychotropic treatment

Related Conditions & MeSH terms

• Ganglion Cysts
• Stroke
• Stroke Basal Ganglia

Intervention

Other:
• Emotional induction
Score (from 1 to 10) rated the felt for each target emotions for the following 6 dimensions: joy, sadness, fear, disgust, anger, no emotion, after the presentation of short sequences of standardized films.

Locations

Country	Name	City	State
France	Centre Hospitalier Régional Universitaire de Brest	Brest

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital, Brest

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	The emotional experience	The emotional response will be compared between patients with focal lesion cores by ischemic or hemorrhagic reached that of healthy participants.; Score (from 1 to 10) rated the felt for each target emotions for the following 6 dimensions: joy, sadness, fear, disgust, anger, no emotion, after the presentation of short sequences of standardized films. Six films are presented, each after a relaxation period after which the basal score is measured.	Baseline
Secondary	The recognition of facial expressions	The facial expression recognition will be compared between patients with focal lesion cores by ischemic or hemorrhagic reached that of healthy participants.; Percentage of recognition of facial emotions expression for each of the following 7 sizes: joy, sadness, fear, surprise, disgust, anger, no emotion; 8 frames per dimensions are presented on a total of 56 facial expressions (Ekman & Friesen, and Karolinska series).	Baseline