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Study of a Neuroprotective Drug to Limit the Extent of Damage From an Ischemic Stroke — MINOS  

Stroke, Acute Clinical Trial

Official title:
Minocycline to Improve Neurologic Outcome in Stroke (MINOS)

Clinical Trial Summary

The primary aim of this study is to find out which of 4 different doses of minocycline are safe and well tolerated so that we will know the optimal dose to test in future patients.

Clinical Trial Description

Minocycline is a widely used antibiotic and is approved by the Food and Drug Administration (FDA) for treatment of infections and acne. However, doctors do not know whether minocycline will work in stroke patients. Its use in stroke patients is experimental. There is a lot of information from experimental stroke studies in animals that minocycline lessens the damage from a stroke and the animals recover better. Since minocycline is generally a very safe drug in humans and does not have a lot of side effects, investigators at Georgia Health Sciences University (formerly the Medical College of Georgia) believe that it might be a safe and effective drug to improve the outcome in patients with stroke. ;

Study Design

Endpoint Classification: Safety Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00630396
Study type Interventional
Source Georgia Regents University
Contact
Status Completed
Phase Phase 1/Phase 2
Start date May 2008
Completion date January 2010
View Details
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