Upper Cervical and Thoracic Chiropractic Adjustment

Stress Clinical Trial

Official title:

Effects of Upper Cervical and Thoracic Chiropractic Adjustments on the Autonomic Nervous System and Perceived Stress Response

Clinical Trial Details — Status: Suspended

Administrative data

• NCT number: NCT05465395
• Other study ID #: I-0020
• Status: Suspended
• Phase: N/A
• Start date: October 12, 2021
• Est. completion date: November 1, 2023

Study information

• Verified date: May 2023
• Source: Life University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The proposed study examines the differences in how the ANS responds to cervical adjustments in comparison to thoracic adjustments. This study is the continuation of a previous study titled Perceived stress and patterns of autonomic function: a protocol development study. Autonomic tests such as HRV, GSR, and the stress surveys will be the primary method of measurement. CareTaker and Biopac devices will provide continual data collection of ECG (for HRV analysis) and GSR throughout the exam and adjustment. Participant's subjective stress levels will be measured through the use of stress questionnaires including the National Stressful Events Survey Acute Stress Disorder Short Scale, the Hamilton Anxiety Rating Scale, and the Connor-Davidson Resilience Scale. The objective of the study is to determine if the location of a chiropractic adjustment will affect the autonomic nervous system in such a way that PNS or SNS activation increases or decreases after the adjustment. Further, the study will continue to examine how the chiropractic adjustment affects the subjective stress response.

Recruitment information / eligibility

• Status: Suspended
• Enrollment: 40
• Est. completion date: November 1, 2023
• Est. primary completion date: November 1, 2023
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• Over the age of 19
• In good health
• Willing to have blood pressure taken
• Willinig to shave a small area of chest hair for placement of a ECG patch
• Consent to a physical exam
• Consent ot chiropractic evaluationa nd 2 adjustments

Related Conditions & MeSH terms

• Stress

Intervention

Procedure:
• Upper Cervical Adjustemnt
Upper cervical adjustement
• Thoracic Adjustemnt
Thoracic adjustment

Locations

Country	Name	City	State
United States	Dr. Sid E. Williams Center for Chiropractic Research	Atlanta	Georgia

Sponsors (1)

Lead Sponsor	Collaborator
Life University

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Caretaker Heart Rate Variability	HRV allows for an understanding of Autonomic (parasympathetic) function, via measuring the interval of R peaks in QRS complexes.	Through study completion, an average of 1 week
Primary	Galvanic Skin Response	Galvanic Skin response gives a strong measure of Sympathetic response via electrical conductivity of perspiration.	Through study completion, an average of 1 week
Primary	Hamilton Anxiety Rating Scale	Measures the severity of anxiety symptoms	Through study completion, an average of 1 week
Primary	NSESSS	Measures PTSD symptoms in people 18 and up.	Through study completion, an average of 1 week
Primary	CD-RISC-25	Measure of adaptability	Through study completion, an average of 1 week