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Stress Disorders, Traumatic clinical trials

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NCT ID: NCT04197102 Suspended - Clinical trials for Post Traumatic Stress Disorder

Use of CBD Oil in the Treatment of Posttraumatic Stress Disorder

Start date: January 15, 2020
Phase: Phase 2
Study type: Interventional

The overarching objective of the proposed project is to test the clinical efficacy of CBD in the treatment of post-traumatic stress disorder using a rigorous double-blind randomized clinical trial methodology. Participants (n=150) meeting full DSM-5 criteria for post-traumatic stress disorder (PTSD) will be randomized to one of 3 treatment arms: (a) CBD -Isolate; (b) CBD-Broad Spectrum; (c) Placebo oil. We predict that patients receiving CBD isolate or CBD Broad Spectrum will show significantly greater improvements in PTSD symptoms and functional impairment at the posttreatment and one-month follow-up relative to patients receiving placebo oil. Additionally, we expect that patients receiving CBD Broad Spectrum will show significantly greater improvements relative to patients receiving CBD Isolate.

NCT ID: NCT02560805 Suspended - Clinical trials for Stress Disorders, Post-Traumatic

Role of Sympathetic Overactivity and Angiotensin II in PTSD and CV

ANG-P
Start date: October 2015
Phase: Phase 2
Study type: Interventional

The purpose of this study is to find out why patients with post-traumatic stress disorder (PTSD) have an increased risk for heart disease and high blood pressure later in life. A second purpose is to find out what causes PTSD patients to have high adrenaline levels during stress. This study will also test if a medicine called losartan improves high adrenaline levels in patients with PTSD and if a certain gene that has to do with high blood pressure might be associated with high adrenaline levels.