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Stomach Neoplasms clinical trials

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NCT ID: NCT01719549 Completed - Gastric Cancer Clinical Trials

Dovitinib for Gastric Cancer With FGFR2 Amplification: GASDOVI-1

Start date: September 2012
Phase: Phase 2
Study type: Interventional

This is a single-center, prospective, single-arm, open-label phase II study

NCT ID: NCT01715233 Completed - Gastric Cancer Clinical Trials

Phase II Study Using CHFR Methylation Status in Patients With Metastatic Esophageal, Gastroesophageal, Gastric Cancer.

Start date: December 2012
Phase: Phase 2
Study type: Interventional

To estimate and compare the response rates in patients treated with mDCF based on methylation status of CHFR.

NCT ID: NCT01711242 Completed - Gastric Cancer Clinical Trials

Trial of Adjuvant XELOX Chemotherapy and Concurrent Capecitabine and Radiotherapy for Resected Gastric Carcinoma

Start date: January 2012
Phase: Phase 2
Study type: Interventional

The objective of the trial is to compare disease-free survival between adjuvant XELOX alone vs XELOX with concurrent capecitabine and radiotherapy in curatively resected gastric cancer patients with D2 dissection.

NCT ID: NCT01679054 Completed - Gastric Cancer Clinical Trials

Cost-minimization Analysis of Gastric Cancer Treatments in Hong Kong

Start date: October 2011
Phase:
Study type: Observational

This is a retrospective cost-minimization analysis study to compare the costs of treatment with EOF vs EOX regimens in patients with gastric cancer (GC) in Hong Kong. Patient baseline characteristics and cost data will be extracted from records and compared.

NCT ID: NCT01671449 Completed - Gastric Cancer Clinical Trials

S-1 and Cisplatin (3 Weekly) Versus S-1 and Oxaliplatin Combination Chemotherapy for Advanced Gastric Cancer

SOPP
Start date: December 2012
Phase: Phase 3
Study type: Interventional

A multicenter, randomized, open-label, phase III trial of S-1 plus cisplatin (3 weekly) versus S-1 plus oxaliplatin chemotherapy for the first-line treatment of advanced gastric cancer

NCT ID: NCT01664494 Completed - Clinical trials for Breast Cancer, Colorectal Cancer, Gastric Cancer

An Observational Study of Xeloda (Capecitabine) in Patients With Metastatic Colorectal Cancer, Colon Cancer in the Adjuvant Setting, Advanced Gastric Cancer or Breast Cancer

Start date: April 2010
Phase: N/A
Study type: Observational

This multi-center observational study will evaluate the use of Xeloda (capecitabine) in patients with metastatic colorectal cancer, colon cancer in the adjuvant setting, advanced gastric cancer and breast cancer in routine clinical practice. Eligible patients receiving treatment with Xeloda according to product label will be followed for up to 10 months.

NCT ID: NCT01662869 Completed - Gastric Cancer Clinical Trials

A Study of Onartuzumab in Combination With mFOLFOX6 in Participants With Metastatic HER2-Negative and MET-Positive Gastroesophageal Cancer

Start date: November 2012
Phase: Phase 3
Study type: Interventional

This randomized, multicenter, double-blind, placebo-controlled study will evaluate the efficacy and safety of onartuzumab (MetMAb) in combination with 5-fluorouracil, folinic Acid, and oxaliplatin (mFOLFOX6) in participants with metastatic human epidermal growth receptor (HER) 2-negative and MET-positive adenocarcinoma of the stomach or gastroesophageal junction. Participants will be randomized in a 1:1 ratio to receive either onartuzumab or placebo in combination with mFOLFOX6. Participants may continue to receive onartuzumab or placebo until disease progression, unacceptable toxicity, participant or physician decision to discontinue treatment.

NCT ID: NCT01659619 Completed - Stomach Cancer Clinical Trials

Effect of Erythromycin Before Endoscopy of Patients With Subtotal Gastrectomy (STG), High Risk of Gastric Stasis

Start date: April 2012
Phase: Phase 2
Study type: Interventional

Erythromycin has a prokinetic effect through Motilin receptor. It evokes migrating motor complex with longer and stronger contraction. In patients with upper gastrointestinal bleeding, It has been shown that erythromycin could clear the stomach of blood, so visual examination could be improved. Frequent food stasis is encounted when we examine patients with subtotal gastrectomy. It is postulated that erythromycin reduce food stasis and help to improve endoscopy in these cases.

NCT ID: NCT01657175 Completed - Quality of Life Clinical Trials

Quality of Life After Oesophageal or Gastric Cancer Surgery

Start date: January 2009
Phase: N/A
Study type: Interventional

This study aim to assess quality of life of patients 0-5 years after oesophageal or gastric cancer surgery and to develop and test an information and support program aiming to enhance the patients quality of life (QOL) after surgery. The project contains 3 part-studies focusing on the patients life after surgery. Data will be collected through focus group interviews and a randomized controlled trial (RCT) study.

NCT ID: NCT01653496 Completed - Stomach Neoplasms Clinical Trials

Compliance to ERAS After Gastric Surgery

ERAS
Start date: July 2012
Phase: Phase 2
Study type: Interventional

The purpose of this study is to prospectively evaluate the overall compliance to the enhanced recovery after surgery (ERAS) program in patients undergoing gastric cancer surgery.