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Clinical Trial Summary

The prognosis of small liver cancer (≤5 cm) with stereotactic body radiotherapy (SBRT) is encouraging, the 1-year local control rate has been reported to be 95-100%, 3-year local control rate about 91%, and 3-year overall survival rate around 70%. So far, there is no randomized controlled study comparing SBRT and surgical treatment for early-stage liver cancer. It is hoped that this study will further compare the efficacy of SBRT and surgery for early stage liver cancer.


Clinical Trial Description

Early stage liver cancer, according to Milan criteria, are chose for this study. The patients are divided into two groups randomly. Patients in group A receive laparoscopic hepatectomy, group B patients receive SBRT.The 3-year progression free survival, 3-year local recurrence free survival, 3- year overall survival and other endpoints events were recorded and analyzed, to assess whether SBRT is non-inferior to surgery. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03609151
Study type Interventional
Source Second Affiliated Hospital, School of Medicine, Zhejiang University
Contact Qichun Wei, MD,PhD
Phone +86 571 87783521
Email qichun_wei@zju.edu.cn
Status Recruiting
Phase N/A
Start date June 30, 2018
Completion date May 31, 2021

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