STEMI Clinical Trial
Official title:
Door To Unloading With IMPELLA CP System in Acute Myocardial Infarction to Reduce Infarct Size (DTU): A Prospective Feasibility Study
Direct active unloading of the left ventricle with the Impella CP System prior to PPCI in patients with ST-elevation myocardial infarction (STEMI) is safe and feasible
A multi-center, prospective, randomized, two-arm feasibility trial to assess the potential
role of unloading with the Impella CP prior to revascularization in reducing infarct size.
The study design includes 1:1 randomization between: 1) Delay Arm: 30 minutes of unloading
with Impella CP prior to primary percutaneous coronary intervention (PPCI); and 2) Immediate
Arm: initiation of Impella CP unloading followed immediately by PPCI.
Study Hypothesis: Direct active unloading of the left ventricle with the Impella CP System
prior to PPCI in patients with ST-elevation myocardial infarction (STEMI) is safe and
feasible
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