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Stellate Ganglion Block clinical trials

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NCT ID: NCT06371131 Recruiting - Clinical trials for Postoperative Nausea and Vomiting

Effect of Stellate Ganglion Block on Postoperative Nausea and Vomiting

Start date: April 17, 2023
Phase: N/A
Study type: Interventional

Postoperative nausea and vomiting is one of the most common postoperative complications second only to postoperative pain. Studies have reported that without any antiemetic prevention treatment, the overall incidence of PONV in surgical operations is up to 20-30%, and the incidence of PONV in high-risk patients such as thyroid surgery is even up to 70-80%. PONV not only increased discomfort and prolonged hospital stay; Severe cases can lead to wound dehysis, acid-base imbalance, water and electrolyte metabolism disorders, seriously affect the prognosis of patients. Although various prevention and treatment measures have been adopted in clinical practice, it still cannot be completely eliminated. Therefore, postoperative nausea and vomiting of thyroid is still a concern in clinical anesthesia work, so it is urgent to explore more simple and effective measures to prevent thyroid PONV. SGB is the injection of local anesthetics into loose connective tissue containing stellate ganglion. It has a clear effect on postoperative analgesia of thyroid surgery, and can play a certain role in preventing thyroid PONV by reducing the application of perioperative opioids. Few studies have reported that the incidence of PONV can be significantly reduced after the application of SGB in patients with thyroid surgery, which provides a certain basis for the prevention of thyroid PONV. Therefore, this study aims to explore the effect of right stellate ganglion block on preventing postoperative nausea and vomiting of thyroid, and to explore the possible mechanism of action.

NCT ID: NCT06300658 Recruiting - Hemodialysis Clinical Trials

Stellate Ganglion Block for Preserving Arteriovenous Fistula in Hemodialysis Patients Undergoing Major Lower Limb Orthopedic Surgery

Start date: March 9, 2024
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the role of stellate ganglion blockade (SGB) for preserving arteriovenous fistula in hemodialysis patients undergoing major lower limb orthopedic surgery.

NCT ID: NCT06244056 Recruiting - Clinical trials for Stellate Ganglion Block

Stellate Ganglion Block as Novel Treatment for Heart Failure Patients

Start date: February 5, 2024
Phase: Phase 2/Phase 3
Study type: Interventional

Stellate Ganglion Block as Novel Treatment for Heart Failure Patients

NCT ID: NCT06189560 Terminated - Dysphagia Clinical Trials

Stellate Ganglion Block: A Breakthrough Treatment for Post-Stroke Pharyngeal Dysphagia

SGB
Start date: June 21, 2022
Phase: N/A
Study type: Interventional

This was a multicenter randomized controlled study. 66 post-stroke patients with pharyngeal dysphagia were randomly allocated to the observation group (n=33) or the control group (n=33). Both groups were provided with comprehensive rehabilitation including routine rehabilitation and swallowing function training. Besides, the observation group additionally underwent the stellate ganglion block (SGB). At admission and after 20-day treatment, Kubota water swallowing test, video fluoroscopic swallowing study (VFSS), and Rosenbek penetration-aspiration scale (PAS) were used to assess swallowing function.

NCT ID: NCT05970146 Recruiting - Clinical trials for Complex Regional Pain Syndromes

Cervical Epidural and Stellate Ganglion Block in Upper Limb Complex Regional Pain Syndrome

Start date: August 1, 2023
Phase: Phase 4
Study type: Interventional

Evaluate the efficacy of two regimens of management in relieving chronic refractory pain in patients with upper limb complex regional pain syndrome after orthopedic trauma

NCT ID: NCT05932485 Recruiting - Clinical trials for Stellate Ganglion Block

Effect of Stellate Ganglion Block on New Atrial Fibrillation After Coronary Artery Bypass Grafting

Start date: June 1, 2023
Phase: N/A
Study type: Interventional

Post-operative new-onset atrial fibrillation (POAF) is one of the most common arrhythmias in adults after direct intracardiac surgery with extracorporeal circulation. The incidence of POAF in coronary artery bypass grafting (CABG) is approximately 30%. POAF can lead to an increased risk of complications such as stroke, heart failure, and acute kidney injury, which not only prolongs the patient's hospital stay, but also increases hospital costs and mortality. operation, extracorporeal circulation, and the patient's underlying conditions (such as age, gender, hypertension, and diabetes), which cause sympathetic activation, inflammatory response, and myocardial ischemia in the organism. The stellate ganglion block (SGB) regulates the sympathetic tone of the innervated nerves and thus the autonomic function of the body. SGB can effectively regulate the sympathetic-parasympathetic imbalance. Also, SGB may exert some anti-inflammatory effects. In this study, ultrasound-guided SGB was used in CABG patients to investigate its effect on the occurrence of POAF.

NCT ID: NCT05652179 Completed - Clinical trials for Stellate Ganglion Block

SGB Reduces the Incidence and Severity of CSA-AKI

Start date: January 10, 2023
Phase: N/A
Study type: Interventional

The incidence of acute kidney injury after cardiopulmonary bypass cardiac surgery is high, which increases postoperative mortality and is not conducive to the prognosis of patients. Stellate ganglion blocks increase renal blood flow, reduce inflammation and stress, and protect the heart muscle. In this study, stellate ganglion block was used to promote rapid recovery of kidney function after cardiopulmonary bypass cardiac surgery.

NCT ID: NCT04800653 Completed - Clinical trials for Stellate Ganglion Block

The Effect of Stellate Ganglion Block on Postoperative Sleep Disturbance and Cognitive Function in Elderly Surgical Patients

Start date: March 1, 2021
Phase: N/A
Study type: Interventional

Postoperative delirium is an acute state of confusion, which is characterized by changes in attention and cognitive functions and fluctuations in consciousness; postoperative cognitive dysfunction is a common central nervous system complication in elderly patients after surgery, often manifested as memory, Obstacles in abstract thinking and orientation are accompanied by a decline in social activity ability. Postoperative delirium and cognitive dysfunction can prolong hospital stay, increase medical expenses, affect postoperative functional recovery, and even increase postoperative mortality. Sleep disorders are a group of diseases that affect the ability to sleep well regularly and cause severe impairment of social and occupational functions. Stellate ganglion block is a selective sympathetic ganglion block, in which a local anesthetic is injected into the loose connective tissue of the neck including the stellate ganglion. There are complex connections between stellate ganglia and multiple brain regions in the brain, which can improve postoperative delirium, cognitive function and sleep disturbance to a certain extent, and have certain guiding significance for postoperative rehabilitation of elderly patients.

NCT ID: NCT04691271 Recruiting - Clinical trials for Aneurysmal Subarachnoid Hemorrhage

Stellate Ganglion Block and Cerebral Vasospasm

BLOCK-CVS
Start date: July 1, 2021
Phase: N/A
Study type: Interventional

At present, cerebral vasospasm (cVS) is the main cause of delayed cerebral infarction (DCI), which leads to high disability and mortality rate after aneurysmal subarachnoid hemorrhage. As a consequence, the key of reducing DCI is to prevent cVS. But unfortunately, despite years of efforts, the prevention and treatment of cVS is still a major clinical dilemma and various ways of treatment are still being explored. Recent studies have shown that stellate ganglion block (SGB) can dilate cerebral vessels and alleviate the impact of existing cVS. However, there is no study to evaluate the effect of early application of SGB on the improvement and prevention of cVS after aSAH.

NCT ID: NCT03756272 Completed - Postmenopausal Clinical Trials

Stellate Ganglion Block to Reduce Hot Flushes

Start date: September 1, 2017
Phase: N/A
Study type: Interventional

To assess the short-term efficacy of stellate ganglion block on hot flush reduction versus sham procedure