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Clinical Trial Summary

This trial will find the best dose of mifepristone when given together with nab-paclitaxel (Abraxane) based on the side effects of the two drugs in patients with advanced breast cancer.

Patients will be randomized to receive nab-paclitaxel with or without mifepristone during the first treatment cycle. After the first cycle, all patients will receive nab-paclitaxel with mifepristone until their disease worsens or they experience an unacceptable side effect.

This study will test up to 4 doses of mifepristone in combination with nab-paclitaxel. The study will first test the lowest dose in a small group of patients and if they do not have bad side effects, higher doses will be tested.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT01493310
Study type Interventional
Source University of Chicago
Contact
Status Completed
Phase Phase 1
Start date November 2011
Completion date May 2018

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