Clinical Trials Logo

Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT03864380
Other study ID # MMT_2018_10
Secondary ID
Status Completed
Phase
First received
Last updated
Start date March 15, 2019
Est. completion date May 6, 2019

Study information

Verified date May 2019
Source Fondation Ophtalmologique Adolphe de Rothschild
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The cardiovascular parameters of prolonged physical exercice have been studied, but very little data is available about the retinal vascularization.

The eye allows in vivo visualization of micro-vascularisation and is considered as an excellent marker of general vascular condition.

The marathon is an intense and prolonged exercise (running 42.195 km) in aerobic environment. Thus the investigators propose to study the vascular parameters of the retina, before and after this physical exercise.

This will allow : 1) to collect information on the physiology of the retinal vascularization to prolonged effort, 2) to detect any retinal damage (haemorrhages, edema, occlusion ...), not known to date.

The results may highlight vascular effects related to retinal hypoxia (venous tortuosity, haemorrhage, venous occlusion, hypoxic edema). Furthermore the results may urge prevention in this sport more and more democratized.

the investigators hypothesized that prolonged physical exercice causes a change in retinal vascularization.


Recruitment information / eligibility

Status Completed
Enrollment 29
Est. completion date May 6, 2019
Est. primary completion date April 14, 2019
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria:

- Person registered at the 2019 Paris Marathon

Exclusion Criteria:

- Ophthalmological disorders making access to the fundus impossible for both eyes

Study Design


Intervention

Diagnostic Test:
Color retinography
Non mydriatic color retinography within 1 month before and within 1 hour after the marathon
OCT-A
Optical Coherence Tomography - Angiography within 1 month before and within 1 hour after the marathon
Blood pressure measurement
Blood pressure measurement within 1 month before and within 1 hour after the marathon

Locations

Country Name City State
France Fondation A de Rothschild Paris

Sponsors (1)

Lead Sponsor Collaborator
Fondation Ophtalmologique Adolphe de Rothschild

Country where clinical trial is conducted

France, 

Outcome

Type Measure Description Time frame Safety issue
Primary Density of retinal vascular plexuses Percentage, Measurement with OCT-A up to 1 hour
See also
  Status Clinical Trial Phase
Recruiting NCT05243134 - The Influence of Anatomic Deformities on the Clinical Efficacy in the Patients With Patellar Dislocation
Terminated NCT04586179 - A Comparison Between Cardiovascular Exercise Modes Following Sport Related Concussion N/A
Not yet recruiting NCT04418063 - Glenohumeral Internal Rotation Deficit in Non-pitcher Overhead Athletic Athletes: Case Series Analysis of Athletes
Not yet recruiting NCT05317130 - A Complex Health Promotion Intervention in Parasport - The Safe & Healthy Parasport Project
Completed NCT05861882 - ASSESSMENT OF THE HANDBALL PLAYERS
Completed NCT05247359 - Neuromuscular Deficits in Jump-Landing Technique in Young Basketball
Completed NCT04780906 - Influence of Wrist Taping on Handgrip Strength in Crossfit Athletes N/A
Completed NCT05254470 - Real-World Experience of Patients Treated for Musculoskeletal Injuries With SAM in Routine Care
Completed NCT04641520 - Shoulder Profile Among Swimmers and Badminton Players
Enrolling by invitation NCT03312504 - Implementing a School Prevention Program to Reduce Injuries Through Neuromuscular Training N/A
Recruiting NCT04121780 - Growth Hormone Replacement Therapy for Retried Professional Football Players Phase 2
Completed NCT04730167 - The Monaco Initiative for Concussion in Motorsport Pilots
Completed NCT03310450 - Tour de Borobudur Troponin Study on Predictors and Synergistic Role of MDA and Hs-CRP Levels
Completed NCT04637607 - Immediate Effect of Non-invasive Auricular Acupoint Stimulation for the Performance and the Meridian Activities of Archery Athletes N/A
Completed NCT04284358 - Does Peer to Peer Learning Facilitated by an iPad Application Help Coaches Learn a Neuromuscular Training Warmup? N/A
Completed NCT04589780 - Is There a Relationship Between the Risk of Injury and Posture in Wrestlers?
Completed NCT05827484 - The Effect of Combined Use of Anti-fibrotic Agent With Platelet Rich Plasma on Skeletal Muscle Healing After Acute Injuries Phase 4
Recruiting NCT05326555 - Dynamic Vision Testing and Concussion Management Dream Team 65
Completed NCT04504929 - The Effectiveness of Dynamic Taping in Preventing Muscle Fatigue N/A
Completed NCT04181242 - Epidemiology of Injuries in Elite Badminton Players: a Prospective Study