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Spinal Cord Neoplasms clinical trials

View clinical trials related to Spinal Cord Neoplasms.

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NCT ID: NCT05096468 Completed - Clinical trials for Perioperative Complication

Esketamine Combined With Pregabalin on Acute Postoperative Pain in Patients Undergoing Resection of Spinal Neoplasms.

Start date: December 1, 2021
Phase: Phase 2/Phase 3
Study type: Interventional

Postsurgical pain is now known to be one of the most common and difficult-to-treat complications of surgery. severe postoperative pain can significantly impair patients' quality of life, social functioning and contribute to excessive health care expenditures. It is worth noting that acute postoperative pain may play a vital role in central sensitization and up-regulation of pain receptors, even factors implicated in the development of CPSP. According to previous studies, the incidence of postoperative pain among patients undergoing spinal surgery was nearly 80%. At the same time, perioperative pain management of patients undergoing spinal surgery has not been clearly. For the past few years, pregabalin and esketamine are becoming important roles in perioperative pain management, lots of studies have shown that these two analgesics might relieve postoperative pain. The aim of this study was to evaluate the acute analgesic effects of esketamine and pregabalin in combination after spinal cord neoplasms resection, so as to find a better way to help the patients undergoing spinal surgery keep away from the acute perioperative pain.

NCT ID: NCT04955522 Completed - Bone Tumor Clinical Trials

Multimodal Imaging Analysis of Spinal Tumors

Start date: December 1, 2019
Phase:
Study type: Observational

In this study, we retrospectively analyzed the imaging data of spinal tumors to find out more imaging features of spinal tumors, in order to provide more accurate reference for the diagnosis of spinal tumors.

NCT ID: NCT04952818 Completed - Spinal Tumor Clinical Trials

The Value of Preoperative Diagnosis and Prognostic Prediction Based on Radiomics of Giant Cell Tumor of Spine

Start date: January 1, 2020
Phase:
Study type: Observational

1. Exploit CT (plain scan), enhanced CT and fMRI based radiomic biomarkers, explore their correlation with the prognostic molecular markers of spinal GCTB(p53/vegf/rank/rankl…), and help accurate diagnosis of GCTB. 2. Exploring a new method of preoperative risk stratification for spinal GCTB, and establishing radiomic model combined with clinical features. Exploring the GCTB biological behavior prediction model and the prognosis prediction of GCTB.

NCT ID: NCT04578691 Completed - Spinal Tumor Clinical Trials

Study to Evaluate the Safety and Clinical Outcome of Using Navigation System in Pedicle Screw Placement in Spine Surgery

Start date: June 29, 2020
Phase: N/A
Study type: Interventional

The research project is testing whether in screw insertion of spine surgery using "Anatase" Spine Surgery Navigation System is at least as safe and accurate as using O-arm assisted spine surgery- Medtronic Stealthstation S7 Treatment Guidance System.

NCT ID: NCT04331431 Completed - Spinal Cord Tumor Clinical Trials

Outcomes of the Intradural Extramedullary Tumors Resection

Start date: April 1, 2008
Phase: N/A
Study type: Interventional

The intradural extramedullary tumors remain curable diseases. Our aim in this study is to evaluate the postoperative status after the tumor resection and compare it to the preoperative status

NCT ID: NCT04219969 Completed - Clinical trials for Spinal Cord Neoplasm

FDG PET-MRI for the Diagnosis of Spinal Cord Lesions

Start date: September 21, 2018
Phase: N/A
Study type: Interventional

To compare the results and understand the possible benefits from FDG-PET/MRI during different scanning time points after FDG, a type of contrast drug, is given.

NCT ID: NCT03585699 Completed - Spinal Tumor Clinical Trials

Percutaneous Fluoroscopic vs CT Guided Core Needle Biopsy for Spinal Infection and Tumor

Start date: November 1, 2016
Phase: N/A
Study type: Interventional

Spinal biopsy is important to obtain culture and histopathological diagnosis in spine infection and tumors. To date, there is no prospective randomized study comparing both techniques. Therefore, the aim of this prospective randomized trial was to evaluate the accuracy, safety and diagnostic outcome of both these techniques.A prospective randomized trial was performed in 60 patients divided equally into fluoroscopic and CT guided spinal biopsy groups. Transpedicular approach was done with 8G core biopsy needle. Specimens were sent for histopathological examinations and cultures. Diagnosis were made based on biopsy results, clinical criteria and disease progression during 6 months follow up. Radiation expose to patients and doctors were measured with optically stimulated luminescence dosimeters (OSLDs).

NCT ID: NCT02790294 Completed - Spinal Tumor Clinical Trials

Optimal Timing of Postoperative Magnetic Resonance Imaging (MRI) in Patients With Extradural Spinal

Start date: August 31, 2016
Phase: N/A
Study type: Interventional

This research study is evaluating suitability of a delayed magnetic resonance imaging (MRI) in management of spine tumors. Currently the standard of care is obtaining an MRI scan in the early postoperative period (within 72 hours after surgery). The purpose of this study is to see if delayed MRI (2 to 3 weeks after surgery) is similar in quality to the earlier MRI. In this study patients will undergo 2 MRIs after the surgery instead of one MRI. Patients will have one MRI about 3 days after the surgery and one MRI about 2-3 weeks after surgery.

NCT ID: NCT02613390 Completed - Spinal Tumor Clinical Trials

Safety Evaluation of Intra-Operative MRI-Based Guidance for Laser Ablation of Epidural Metastasis

Start date: December 18, 2015
Phase: N/A
Study type: Interventional

The goal of this clinical research study is to learn about the safety and accuracy of using MRI as a guidance system during laser ablation surgery of tumors that have spread to the spine.

NCT ID: NCT02494622 Completed - Clinical trials for Spinal Cord Neoplasms

Alternative Treatment of Giant Spinal Schwannomas

Start date: January 2008
Phase: N/A
Study type: Observational

Schwannomas are benign tumors that can reach giant sizes. The diagnosis and treatment of these cases differ from those of small schwannomas. The aim of this study was to review the diagnoses and surgical approach characteristics of the giant spinal schwannomas (GSS) of patients who underwent surgery.