Clinical Trials Logo
  1. Home
  2. Spinal Tumor
  3. NCT04952818

The Value of Preoperative Diagnosis and Prognostic Prediction Based on Radiomics of Giant Cell Tumor of Spine

Spinal Tumor Clinical Trial

Official title:
Radiomics Based on Preoperative Imaging of Giant Cell Tumor of the Spine to Predict the Early Recurrence and Survival of Giant Cell Tumor of the Spine After Surgery, and the Expression Levels of P53, VEGF, RANK, RANKL and Other Prognostic-related Molecular Markers.

Clinical Trial Summary

1. Exploit CT (plain scan), enhanced CT and fMRI based radiomic biomarkers, explore their correlation with the prognostic molecular markers of spinal GCTB(p53/vegf/rank/rankl…), and help accurate diagnosis of GCTB. 2. Exploring a new method of preoperative risk stratification for spinal GCTB, and establishing radiomic model combined with clinical features. Exploring the GCTB biological behavior prediction model and the prognosis prediction of GCTB.

Clinical Trial Description

This study intends to conduct a systematic review of patients with spinal GCTB who have undergone standardized imaging (CT or MRI) in our hospital since 2006 to obtain case samples, conduct standardized clinical and imaging data extraction and analysis, and fully integrate histopathology and clinical follow-up results. To preliminarily explore the value of postoperative imaging-based radiomics markers in the preoperative precise diagnosis of spinal GCTB, risk stratification and prediction of tumor biological behavior. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04952818
Study type Observational
Source Peking University Third Hospital
Contact
Status Completed
Phase
Start date January 1, 2020
Completion date March 1, 2020
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT03668522 - Clinical Research of H3F3AK27M in Spinal Glioma and Its Impact on TMZ Chemoradiotherapy
Active, not recruiting NCT03956537 - PMCF Neo Pedicle Screw and Cage Systems
Completed NCT03585699 - Percutaneous Fluoroscopic vs CT Guided Core Needle Biopsy for Spinal Infection and Tumor N/A
Completed NCT04578691 - Study to Evaluate the Safety and Clinical Outcome of Using Navigation System in Pedicle Screw Placement in Spine Surgery N/A
Withdrawn NCT03893110 - Carbon PEEK Versus Titanium Pedicle Screws in the Treatment of Spinal Tumors N/A
Not yet recruiting NCT06161974 - Study of Olutasidenib and Temozolomide in HGG Phase 2
Completed NCT01624220 - A Prospective Study Using Implanted Fiducial Markers to Assess Treatment Accuracy and Esophageal Toxicity in Spinal Stereotactic Body Radiation Therapy N/A
Not yet recruiting NCT05369689 - Stereotactic Radiosurgery Prognosis Assessment for Spinal Tumors Based on Radiomics
Recruiting NCT05296889 - Post-Market Clinical Follow-Up Study on the Safety and Performance of Ennovate® Cervical
Completed NCT02252185 - A Clinical Study of a Spine Fusion System in Vertebral Body Fusion Surgery N/A
Recruiting NCT06120426 - En Bloc Resection Versus Separation Surgery Combined With Radiotherapy for the Treatment of Spinal Oligometastatic Tumor.
Recruiting NCT05170815 - Clariance ErYs Registry
Active, not recruiting NCT03052738 - Medical Marijuana in the Pediatric Central Nervous System Tumor Population
Recruiting NCT03398915 - The European Robotic Spinal Instrumentation (EUROSPIN) Study
Recruiting NCT04217525 - Duke Spine Outcome Study (DSOS)
Enrolling by invitation NCT05106179 - The Efficacy and Safety of Beta-blockers Drugs in Adults With Spinal Hemangioma Phase 4
Completed NCT02613390 - Safety Evaluation of Intra-Operative MRI-Based Guidance for Laser Ablation of Epidural Metastasis N/A
Not yet recruiting NCT05396222 - A Prospective Study of the Safety and Efficacy of 3D-printed Non-rigid Biomimetic Implant in Cervical and Thoracolumbar Spine N/A
Completed NCT02790294 - Optimal Timing of Postoperative Magnetic Resonance Imaging (MRI) in Patients With Extradural Spinal N/A
Recruiting NCT05631002 - Chemical Shift Encoding-based Water-fat Magnetic Resonance Imaging in Spinal Tumors